The most common side effects: dizziness, headache, fatigue, diarrhea, dry cough, nausea.
From the cardiovascular system: marked decrease in blood pressure, chest pain, rarely - orthostatic hypotension, tachycardia, bradycardia, worsening of symptoms of heart failure, violation of atrioventricular conduction, myocardial infarction, heart palpitations.
From the central nervous system: lability of mood, confusion, paresthesia, drowsiness, convulsive twitching of the muscles of the limbs and lips, rarely - asthenic syndrome.
On the part of the hematopoiesis system: leukopenia, neutropenia, agranulocytosis, thrombocytopenia, anemia (decrease in the concentration of hemoglobin, hematocrit, erythrocytopenia).
Laboratory indicators: hyperkalemia, hyponatremia, rarely - increased activity of "hepatic" enzymes, hyperbilirubinemia, increased levels of urea and creatinine.
From the respiratory system: dyspnea, bronchospasm.
From the digestive tract: dry mouth, anorexia, dyspepsia, changes in taste, abdominal pain, pancreatitis, hepatocellular or cholestatic jaundice, hepatitis.
From the skin: urticaria, increased sweating, pruritus, alopecia, photosensitivity.
From the genitourinary system: impaired renal function, oliguria, anuria, acute renal failure, uremia, proteinuria, decreased potency.
Allergic reactions: angioedema, edema of the face, extremities, lips, tongue, epiglottis and / or larynx, skin rashes, itching, fever, positive results of the test for antinuclear antibodies, increased erythrocyte sedimentation rate (ESR), eosinophilia, leukocytosis.In very rare cases, there is an aggressive angioedema.
Other: myalgia, arthralgia / arthritis, vasculitis.