Patients who, together with magnesium sulfate, use other medicines should inform the doctor about this.
Strengthens the effect of other drugs that depress the central nervous system.
Cardiac glycosides increase the risk of conduction disruption and atrioventricular blockade (especially with simultaneous intravenous administration of calcium salts). Muscle relaxants and nifedipine strengthen the neuromuscular blockade.
With the joint use of magnesium sulfate for parenteral administration with other vasodilators, an increase in the hypotensive effect is possible.
Barbiturates, narcotic analgesics, hypotensive drugs increase the likelihood of oppression of the respiratory center.
It interferes with the absorption of antibiotics of the tetracycline group, weakens the action of streptomycin and tobramycin.
Calcium salts reduce the effect of magnesium sulfate.
Pharmaceutically incompatible (forms a precipitate) with calcium preparations, carbonates,bicarbonate and phosphate of alkali metals, clindamycin phosphate, hydrocortisone sodium succinate, polymyxin In sulfate, procaine hydrochloride, salicylates and tartrates, salts of arsenic acid, barium, strontium.
When the magnesium ions are higher than 10 mmol / ml in mixtures for complete parenteral nutrition, fat emulsion separation is possible.