Active substanceDioxomethyltetrahydropyrimidineDioxomethyltetrahydropyrimidine
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  • Dosage form: & nbspsponge
    Composition:1 g of the drug contains active substances: collagen, substance-solution 2% - 47.5 g (0.95 g of dry collagen), dioxomethyltetrahydropyrimidine (methyluracil) - 0.05 g.
    Description:Plates of white color of a porous structure with a specific smell and with a relief surface, a thickness of 7 to 13 mm, dimensions (50 ± 5) x (50 ± 5) mm, (90 ± 10) x (90 ± 10) mm. The drug easily absorbs moisture.
    Pharmacotherapeutic group:Stimulator of tissue repair
    ATX: & nbsp

    D.11.A.X   Other preparations for the treatment of skin diseases

    L.03.A.X   Other immunostimulants

    Pharmacodynamics:

    Dioxomethyltetrahydropyrimidine (methyluracil) normalizing the nucleic exchange, accelerates the processes of cellular regeneration in wounds, growth and granulation maturation of tissue, epithelization, has an anti-inflammatory effect. Collagen accelerates the growth, maturation and structuring of granulation tissue, stimulates epithelization. Reduces the risk of formation of hypertrophic scars. When applied to the wound, the sponge adheres tightly to its surface, absorbs the wound detachable, swells and gradually loses, releasing the methyluracil entering it. Collagen is exposed in a wound of gradual biodegradation - lysis and resorption.

    The sponge prevents the loss of fluid from the surface of the wound, preventing it from drying out and protects the wound from external influences and infection.

    Indications:Trophic ulcers, bedsores, deep and long-lasting non-healing wounds, superficial skin burns.
    Contraindications:Hypersensitivity. The presence of excess granulation in the wound.
    Carefully:Children under 3 years.Pregnancy and lactation.
    Dosing and Administration:Outwardly. The wound must first be treated with an antiseptic solution and the remains of necrotic tissue removed. In the presence of purulent discharge drug is recommended to combine with antiseptic solutions, for example, hydroxymethylquinoxaline dioxide (dioxidin), wetting a sponge. The sponge is removed from the package immediately before use, observing the rules of asepsis. The number and size of the sponge is selected, according to the area and depth of the wound. If necessary, the sponge is cut into pieces of the correct size and shape. The sponge should fit tightly to the entire surface of the wound and extend beyond its edges by 1-1.5 cm. If necessary, cover the sponge with a bandage or two layers of gauze. The frequency of dressings depends on the depth and area of ​​the wound surface, the intensity of exudation and the presence of necrotic masses. The condition of the wound is monitored once a day with a small amount of detachable and 2 times a day with abundant. A sponge completely impregnated with a detachable wound is removed and replaced with a new one. If the sponge in the wound is dry, the dressing is recommended to be done once in 2 -3 days, during this period the sponge is lysed.If the sponge did not resolve, and there is no indication for the dressing (pain, burning sensation in the wound, accumulation of purulent exudate, the presence of allergic reactions), it is not removed. The course of treatment is carried out until complete epithelialization, or filling the wound with granulation tissue to the full depth.
    Side effects:Allergic reactions in the form of itching, hyperemia, short-term burning. Pain in the area of ​​the wound (due to its contraction with the drying of the sponge).
    Interaction:The drug is compatible with external applications of antibacterial, antiseptic and anesthetic drugs.
    Special instructions:To eliminate pain from tightening the wound with a sponge, it is necessary, without removing the sponge, to moisten it with a 0.25% solution of procaine, or with an aqueous 0.02% solution of nitrofural.
    Form release / dosage:Sponge in the sizes (50 ± 5) х (50 ± 5) mm on 1 piece. and (90 ± 10) x (90 ± 10) m.
    Packaging:

    1 pc. is packaged hermetically in a two-layered bag of polyethylene film, or in a container of polyvinylchloride film and aluminum foil with a heat-sealable coating, or in a soft container made from polyform film and laminated paper, or only from Polyform film.

    A two-layer bag or container, together with the instructions for use, is placed in a cardboard box.

    Storage conditions:In a dry, dark place at a temperature of 10 to 30 C.Keep out of the reach of children.
    Shelf life:4 years. Do not use at the end of the expiration date printed on the package.
    Terms of leave from pharmacies:On prescription
    Registration number:P N002011 / 01
    Date of registration:19.11.2008 / 27.07.2010
    Expiration Date:Unlimited
    The owner of the registration certificate:BELKOZIN - LUZHSKY FACTORY, OJSC BELKOZIN - LUZHSKY FACTORY, OJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp11.05.2018
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