Mefifin® belongs to the group of compounds of 3-hydroxypyridine and succinic acid and has antioxidant, antihypoxic, membrane-stabilizing, nootropic, stress-protective, anticonvulsant and anxiolytic effects.
Mefifin® acts as a free radical inhibitor, inhibits the processes of lipid peroxidation, increases the activity of the antioxidant system of enzymes, restores the structure and function of membranes disrupted in various pathologies, modulates membrane-bound enzymes (calcium-independent phosphodiesterase, adenylyl cyclase, acetylcholinediesterase), ion channels, receptor complexes , including benzodiazepine, GABA, acetylcholine; improves the transport of neurotransmitters, synaptic transmission and the interconnection of brain structures. Increases the content of the brain dopamine.
The mechanism of action of Mexifin® is due to its ability to enhance the compensatory activation of aerobic glycolysis. It reduces the degree of inhibition of oxidative processes in the Krebs cycle under conditions of hypoxia, increasing the content of ATP and creatine phosphate; contributes to the preservation of the structural and functional organization of biomembranes.
Mefifin® improves cerebral metabolism and blood supply to the brain, corrects disturbances in the regulatory and microcirculatory systems, suppressing the constriction of arterioles and precapillaries; improves rheological properties of blood, reducing aggregation of platelets, stabilizing the membrane structures of blood cells (red blood cells and platelets), preventing hemolysis; improves the immune system. Mefifin® has an anti-atherogenic effect, causing a regression of atherosclerotic changes in the arteries, reducing the level of cholesterol and low-density lipoproteins, restoring lipid homeostasis.
Mefifin® improves the working capacity and resistance of the organism to the effects of various extreme damaging factors in oxygen-dependent pathological conditions (shock, stress, hypoxia and ischemia, cerebral circulation,physical and mental overload), intoxication with alcohol and antipsychotic drugs (neuroleptics).