The dose of Pangrol® 25000 is selected individually depending on the severity of the disease, as well as the volume and composition of the food taken.
If there is no other indication, adults it is recommended to take 1-2 capsules of Pangrol® 25000 during each meal, swallowing whole capsules (do not chew), with a sufficient amount of liquid (for example, a glass of water). If a whole patient capsule is difficult to take (for example, in young children or elderly patients), you can pour its contents, for example, into a glass, opening the capsule by separating the lid from the body, and then taking the contents (mini tablets) liquid or add to liquid food that does not require chewing (for example, apple puree or fruit juice). Mixture of mini-tablets with food or liquid is not to be stored (taken immediately after preparation).
An increase in the dose of the drug should be carried out only under the supervision of the doctor, while focusing on the dynamics of symptoms (for example, reduction of steatorrhea, easing of pain in the abdomen).
The daily dose of enzymes, amounting to 15000-20000 lipase units / kg body weight, is not recommended.
The duration of the course of treatment is determined by the doctor and depends on the course of the disease.
Children the dosing regimen and the duration of treatment are determined by the doctor depending on the severity of the disease and the composition of the food at a rate of 500 - 1000 lipase units / kg of the body weight of the child for each meal.
Application for cystic fibrosis
The dose of Pangrol® 25000 depends on the body weight and should be at the beginning of treatment 1000 lipase units / kg for each meal for children under 4 years, and 500 lipase units / kg at each meal for children over 4 years.
The dose of the drug should be selected individually, depending on the severity of the disease, under the control of the steatorrhea and the support of an optimal diet. In most patients, the dose should not be more than 10,000 lipase units / kg body weight per day or 4000 lipase units / g of consumed fat.