Pancreatin - instructions for use, dose, side effects, contraindications

Excipients: povidone (polyvinylpyrrolidone low molecular weight) - 15.0 mg, calcium stearate - 3.2 mg, lactose monohydrate - until the nucleus tablets weighing 320.0 mg;

shell: methacrylic acid and ethyl acrylate copolymer (colliquite MAE 100P) - 21.3 mg, titanium dioxide [171] - 3.47 mg, macrogol (polyethylene oxide 4000) 3.2 mg, povidone (low molecular weight polyvinylpyrrolidone) 2.0 mg, dye azorubin [122] - 0.03 mg.

Description:biconvex tablets, covered with a pink coating

Pharmacotherapeutic group:digestive enzyme.

ATX: & nbsp

A.09.A.A Enzyme preparations

A.09.A.A.02 Pancreatin

Pharmacodynamics:Digestive enzyme agent, replenishes the deficiency of pancreatic enzymes, has proteolytic, amylolytic and lipolytic effects.Included in the composition of pancreatic enzymes (lipase, alpha-amylase, trypsin, chymotrypsin) promote the breakdown of proteins to amino acids, fats to glycerol and fatty acids, starch to dextrins and monosaccharides, improve the functional state of the gastrointestinal tract, and normalize the digestive processes. Trypsin suppresses the stimulated secretion of the pancreas, giving an analgesic effect. Pancreatic enzymes are released from the dosage form in the alkaline medium of the small intestine. protected from the action of gastric juice shell. The maximum enzymatic activity of the drug is observed 30-45 minutes after oral administration.

Indications:

Substitution therapy with exocrine pancreatic insufficiency, gland: chronic pancreatitis, pancreatectomy, condition after irradiation, dyspepsia, cystic fibrosis; flatulence, diarrhea of non-infectious genesis. Disturbance of the assimilation of food (state after resection of the stomach and small intestine); to improve the digestion of food in individuals with normal gastrointestinal function (gastrointestinal tract) in case of errors in nutrition (eating fatty foods, large amounts of food,irregular feeding) and with violations of masticatory function, sedentary lifestyle, prolonged immobilization. Remkheld's syndrome (gastrocardial syndrome). Preparation for X-ray examination and ultrasound (ultrasound) of the abdominal organs.

Contraindications:

Acute pancreatitis, exacerbation of chronic pancreatitis, hypersensitivity to the components of the drug.

Dosing and Administration:Inside, during or after a meal, swallowing whole, squeezed large amounts of liquid (water, fruit juices). The dose of the drug (in terms of the protease) depends on the age and degree of pancreatic insufficiency.

For adults single dose is 60-120 ED (2-4 pills). Children are prescribed the drug in the following doses: at the age of 6-7 years - 30 ED (1 tablet); 8-9 years - 30-60 units (1-2 pills); 10 - 14 years - 60 ЕD (2 tablets).

Duration of treatment can vary from several days (with digestion disorders, inaccuracies in the diet) to several months and even years (if necessary, permanent replacement therapy).

Side effects:The drug is usually well tolerated, but in some cases, allergic reactions can occur, rarely diarrhea or constipation, nausea, discomfort in the epigastric region.With prolonged use in high doses, hyperuricosuria, when high doses are used in patients with cystic fibrosis, strictures in the ileocecal region and in the ascending colon.

Overdose:

Symptoms: hyperuricosuria, hyperuricemia. Children have constipation.

Treatment: withdrawal of the drug, symptomatic therapy.

Interaction:

Reduces the absorption of iron.

Special instructions:

With prolonged use, iron preparations are simultaneously prescribed.

Form release / dosage:Tablets, covered with enteric coating, 30 units.

Packaging:

For 10 tablets in a planar cell pack, 60 tablets in a polymer bottle. 6 contour squares or 1 bottle of polymer together with instructions for use in a pack of cardboard.

Storage conditions:

In a dry place, at a temperature not exceeding 20 ° С.

Keep out of the reach of children.

Shelf life:

2 years.

Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:P N001196 / 01

Date of registration:14.08.2008

The owner of the registration certificate:FARMPROJECT, CJSC FARMPROJECT, CJSC Russia

Manufacturer: & nbsp

FARMPROJECT, CJSC Russia

Information update date: & nbsp19.08.2015

Illustrated instructions

Instructions

Pancreatin (Pancreatin)