Active substanceSulfacetamideSulfacetamide
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  • Dosage form: & nbspEye drops.
    Composition:
    1 ml contains:

    active substance - sodium sulfacetamide monohydrate (sodium sulfacyl) (in terms of dry matter) - 100 mg (10% preparation), 200 mg (20% drug);

    Excipients - sodium disulfite (sodium metabisulphite), sodium hydroxide solution (sodium hydroxide) 1 M, purified water - up to 1 ml.
    Description:Transparent colorless or slightly colored liquid.
    Pharmacotherapeutic group:Antimicrobial agent - sulfonamide.
    ATX: & nbsp

    A.07.A.B   Sulfonamides

    Pharmacodynamics:Antimicrobial bacteriostatic agent, sulfanilamide. The mechanism of action is associated with competitive antagonism with PABA and inhibition of dihydropteroate synthetase, which leads to a disruption in the synthesis of dihydrofolic acid and, ultimately, its active metabolite of tetrahydrofolic acid, necessary for the synthesis of purines and pyrimidines.
    sodium-DIA Sulfatsil active against Gram-positive and Gram-negative cocci, Escherichia coli, Shigella spp., Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces israelii, Toxoplasma gondii.
    Pharmacokinetics:Penetrates the tissues and fluid eyes. Absorbed into the systemic bloodstream through an inflamed conjunctiva.
    Indications:
    - Conjunctivitis;

    - Blepharitis;

    - Purulent corneal ulcer;

    - Prevention and Treatment of Infections in newborns;

    - Gonococcal and chlamydial eye disease in adults.
    Contraindications:Individual hypersensitivity to the components of the drug.
    Pregnancy and lactation:Sufficient experience in the use of the drug during pregnancy, breast-feeding is not.It is possible to use sulfacetamide to treat pregnant and lactating mothers as prescribed by the doctor if the expected curative effect exceeds the risk of possible side effects.
    Dosing and Administration:
    Bury in a conjunctival bag for 1-2 drops 5-6 times a day. For the prevention of blennery in newborns - 2 drops in each conjunctival sac immediately after birth and 2 drops - after 2 hours.
    Side effects:Burning, lacrimation, itching, itching in the eyes, allergic reactions.
    Overdose:Data on drug overdose are absent.
    Interaction:Combined use with novocaine and dicaine reduces the bacteriostatic effect of sodium sulfacyl. The incompatibility of sulfacyl sodium is observed when it is used together with silver salts.
    Special instructions:Patients who are hypersensitive to furosemide, thiazide diuretics, sulfonyl urea or inhibitors of carbonic anhydrase, may have increased sensitivity to sulfacetamide.
    Form release / dosage:Eye drops 10%.
    Packaging:
    For 5 or 10 ml of Sulfacil sodium-DIA drops eye (10% or 20% solution of sulfacetamide) in bottles of glass or polypropylene, sealed with stoppers, rubber and rinsed with aluminum caps,or in bottles of droppers, polyethylene or polypropylene, hermeticized droppers and screw caps.
    1 bottle complete with a lid-dropper or without it, together with instructions for use in a cardboard bundle or in a contoured package packed in a heat-seal bag.
    1 vial of a dropper along with instructions for use in a cardboard bundle or in a contoured package packed in a thermo-sealable bag.
    50 bottles or bottles of IV drips intended for hospital, together with 10-20 instructions for use in a cardboard box.
    Storage conditions:
    At a temperature of no higher than 25 ° C in a protected from light.

    Keep out of the reach of children. Do not freeze.
    Shelf life:2 years. Do not use after the expiration date stated on the package.
    Terms of leave from pharmacies:Without recipe
    Registration number:P N001943 / 01-2002
    Date of registration:30.10.2008
    The owner of the registration certificate:DIAPHARM Institute of Molecular Diagnostics, ZAO DIAPHARM Institute of Molecular Diagnostics, ZAO Russia
    Manufacturer: & nbsp
    Information update date: & nbsp03.09.2015
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