Intramuscularly (in / m), intravenously (iv).
In / in (drip at a speed of 60-80 cap / min, jet - slowly, for 3-5 minutes).
In / in 5-7 days, then, if necessary, continue treatment, go to the / m introduction.
The following are the total doses of ampicillin and sulbactam (in a 2: 1 ratio).
With a light infection, 1.5-3 g / day in 2 injections; at an average flow - 3-6 g / day in 3-4 injections; at heavy currents -12 g / day in 3-4 injections.
With uncomplicated gonorrhea - 1.5 grams, once.
For the prevention of surgical infections - 1,5-3 g during anesthesia; then within 24 hours after the operation in the same dose every 6-8 hours.
Children - in a daily dose of 150 mg / kg (100 mg / kg ampicillin and 50 mg / kg sulbactam); multiplicity - 3-4 times a day.
In children from 1 month to 12 years of age (or weighing up to 40 kg) in the treatment of severe infections, the dose is increased to 300 mg / kg per day.
Newborns under the age of 1 week and premature babies are usually prescribed dose 75 mg / kg (50 mg / kg ampicillin and 25 mg / kg sulbactam) per day every 12 hours.
A course of treatment - 5-14 days (if necessary, can be extended). After normalization of temperature and disappearance of other pathological symptoms, treatment is continued for another 48 hours.
If the kidney function is impaired and the creatinine clearance is lower than 30 ml / min, it is advisable to increase the intervals between administrations to 12-24 hours.
The solution for parenteral use is prepared immediately before use. To prepare the solution for intramuscular injection, 2 or 4 ml of water for injection, 0.5 % solution of procaine or 0.9 % solution of sodium chloride.
For the / m introduction, a dilution of 0.5 % lidocaine solution.
For intravenous administration, a single dose is dissolved in 0.9 % solution of sodium chloride or 5 % a solution of dextrose in a volume of 10 to 200 ml.