Allergic reactions: urticaria, skin hyperemia, angioedema, rhinitis, conjunctivitis, fever, arthralgia, eosinophilia, rarely rash, itching, rarely - bronchospasm, eosinophilia, serum sickness, anaphylactic shock, very rare: erythema polymorph, Stevens-Johnson syndrome, toxic epidermal necrolysis.
From the gastrointestinal tract: nausea, vomiting, decreased appetite, diarrhea, pseudomembranous enterocolitis, impaired liver function (increased activity of "liver" transaminases, cholestatic jaundice).
On the part of the organs of hematopoiesis and the system of hemostasis: anemia, hemolytic anemia, leukopenia, neutropenia, lymphopenia, thrombocytopenia and eosinophilia.
From the nervous system: drowsiness, malaise, headache, very rarely reported the appearance of seizures.
Laboratory indicators: transient increase in activity of alanine aminotransferase (ALT) and aspartic aminotransferase (ACT), Hyperbilirubinemia, azotemia, increased urea concentration, hypercreatininaemia.
Other: Very rarely reported cases of interstitial nephritis, with long-term treatment - superinfection caused by drug-resistant microorganisms (candidiasis).