From the digestive system: nausea, vomiting, diarrhea, abdominal pain, pseudomembranous colitis.
From the side of the central nervous system: headache, dizziness, fatigue, sleep disorders, nightmares, hallucinations, fainting, vision disorders.
Co side of the urinary system: crystalluria, interstitial glomerulonephritis, dysuria, polyuria, albuminuria, hematuria, transient increase in serum creatinine.
Co hematopoiesis side: eosinophilia, leukopenia, neutropenia, a decrease in the number of platelets.
Co cardiovascular system: tachycardia, heart rhythm disturbances, arterial hypotension.
Allergic reactions: skin itching, urticaria, Quincke's edema, Stevens-Johnson syndrome, arthralgia.
Adverse reactions associated with chemotherapeutic action: candidiasis.
Co side of laboratory indicators: increased activity of hepatic transaminases, alkaline phosphatase, lactate dehydrogenase, bilirubin, increased urea concentration, creatinine.
Other: arthralgia; rarely - photosensitivity.