ARTHRA Chondroitin - instructions for use, dose, side effects, contraindications

Description:Opaque, from white to almost white, hard gelatin capsules. The contents of capsules are powder from white to almost white.A specific odor is allowed.

Pharmacotherapeutic group:Reparation of tissue stimulant

ATX: & nbsp

M.01.A.X.25 Chondroitin sulfate

Pharmacodynamics:Affects the metabolic processes in the hyaline and fibrous cartilage, stimulates the biosynthesis of glycosaminoglycans. Slows the resorption of bone tissue and reduces calcium loss, accelerates the recovery of bone tissue. It reduces degenerative changes and stimulates the restoration of the cartilaginous tissue of the joints, relieves pain in the joints and spine, increases the mobility of the joints, takes part in the formation of bone tissue, ligaments, maintaining the elasticity of the vascular wall. In the treatment of degenerative diseases of the joints and spine (osteoarthrosis and osteochondrosis) alleviates the symptoms of the disease and reduces the need for non-steroidal anti-inflammatory drugs (NSAIDs). Slows the resorption of bone tissue and reduces calcium loss, accelerates the recovery of bone tissue, which contributes to the enhancement of reparative processes in fractures and paradontopathies. The therapeutic effect persists for a long time after the end of the course of treatment.

Pharmacokinetics:More than 70% of chondroitin sulfate is absorbed in the digestive tract. Bioavailability of the drug is 13%. With a single admission of the medial therapeutic dose, the maximum concentration in the plasma is noted after 3-4 hours, in the synovial fluid after 4-5 hours. Absorbed in the GIT, the drug accumulates in the synovial fluid. It is excreted by the kidneys.

Indications:Osteoarthritis of peripheral joints, osteochondrosis of the spine.

Contraindications:Hypersensitivity to the drug, children under 15 years.

Carefully:Bleeding and a tendency to bleeding, thrombophlebitis.

Pregnancy and lactation:

It is not recommended to take during pregnancy and during breastfeeding due to lack of data.

Dosing and Administration:

Inside, washing down with water.

250 mg capsules: inside, adults 2 capsules 2 times a day.

Capsules of 500 mg: by mouth, adults 1 capsule 2 times a day.

Capsules of 750 mg: by mouth, adults 1-2 capsules per day.

The recommended duration of the initial course of treatment is 6 months. The period of action of the drug after its cancellation is 3-5 months. The duration of repeated courses of treatment is set by the doctor.

Precautions for use:

Do not exceed the recommended dose.

Caution should be given to patients with bleeding, as well as patients with a tendency to bleeding.

Side effects:In rare cases, allergic reactions, abnormalities on the part of the gastrointestinal tract (nausea, vomiting) are possible.

Overdose:

Cases of overdose are unknown.

Treatment: gastric lavage, symptomatic therapy.

Interaction:

With the simultaneous use of the drug with other drugs, it is possible to increase the effect of indirect anticoagulants, antiplatelet agents, fibrinolytics. The drug is compatible with non-steroidal anti-inflammatory drugs (NSAIDs) and glucocorticosteroids.

Form release / dosage:Capsules 250 mg, 500 mg, 750 mg.

Packaging:

For 60 capsules in a bottle of polyethylene with a screw cap made of the same material and a safety valve made of foil and a protective strip of polyethylene. The label is attached to the bottle, the bottle is tightened with a polyethylene film and, together with the instruction for use, is placed in a cardboard box.

For 15 capsules in an aluminum foil / PVC blister. 4, 6 or 8 blisters together with instructions for use are placed in a cardboard box.

Storage conditions:

In a dry place, at a temperature of 10 - 30 ° C. Keep out of the reach of children.

Shelf life:3 years. Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LS-001701

Date of registration:05.12.2011

Expiration Date:Unlimited

The owner of the registration certificate:Unipharm, Inc.Unipharm, Inc. USA

Manufacturer: & nbsp

UNIPHARM ,, Inc. USA

Representation: & nbspUNIFARM, Inc. UNIFARM, Inc. USA

Information update date: & nbsp13.09.2017

Illustrated instructions

Instructions

ARTRA® Chondroitin (ARTRA® Chondroitin)