Arthravir-Inkampharm - instructions for use, dose, side effects, contraindications

Affects the exchange processes in the hyaline cartilage, reduces the degenerative changes in the cartilage tissue of the joints, stimulates the biosynthesis of glucosaminoglycans. In the treatment ARTRAVIR®-INCAMPHAR®® reduces soreness and improves mobility of affected joints.

Pharmacodynamics:

Chondroitin sulfate is a natural component of cartilaginous tissue.

Degenerative changes in the joints are accompanied by its loss. The drug ARTRAVIR ® - INKAMFARM ® serves as a substitute therapy.In the treatment of degenerative joint changes accompanied by a secondary synovitis, a positive effect is observed after 2-3 weeks after the start of the drug application. The pain in the joints decreases, the clinical manifestations of the reactive synovitis disappear, the volume of movements in the affected joints increases.

The therapeutic effect persists for a long time after the end of the course of treatment.

Pharmacokinetics:

Chondroitin sulfate is easily absorbed. Already 30 minutes after intramuscular injection, it is found in the blood in significant concentrations: the maximum concentration is reached after 1 hour; then its content within 2 days gradually decreases.

Chondroitin sulfate accumulates mainly in the cartilaginous tissue that forms the joints. The synovial membrane is not an obstacle to its penetration into the joint cavity. 15 minutes after intramuscular injection chondroitin sulfate is found in the synovial fluid, then it enters the articular cartilage, where its content reaches a maximum after 48 hours.

Indications:

Degenerative diseases of the joints and spine: osteoarthritis, intervertebral osteochondrosis.

Contraindications:

Hypersensitivity to the drug, a child's age, a tendency to bleeding, thrombophlebitis.

Pregnancy and lactation:

At present, there are no data on the use of Artravir®-Inkamparm® during pregnancy and lactation, and also in children.

Dosing and Administration:

Enter intramuscularly 1 ml every other day. With good tolerability, the dose is increased to 2 ml, starting with the fourth injection. The course of treatment is 25-30 injections.

If necessary, it is possible to conduct repeat courses in 6 months.

Side effects:

Allergic reactions and hemorrhages at the injection site are possible. In these cases, the drug is canceled.

Overdose:

At present, cases of an overdose of chondroitin sulfate have not been reported.

Interaction:

ARTRAVIR ® - INCAMPHARM ® is able to strengthen the effect of indirect anticoagulants, antiplatelet agents, fibrinolytic agents, which requires more frequent monitoring of blood coagulation indicators when combined with the use of drugs.

Effect on the ability to drive transp. cf. and fur:

ARTRAVIR ® - INCAMPHARM ® does not affect the ability to drive vehicles and the ability to engage in potentially hazardous activities,requiring increased concentration of attention and speed of psychomotor reactions.

Form release / dosage:

Solution for intramuscular injection, 100 mg / ml.

Packaging:

By 1 or 2 ml into ampoules of neutral glass or glass of the first hydrolytic class with a break point or a kink ring.

By 5 ampoules in a plastic pallet or contour mesh packaging.

For 1, 2 plastic pallets or 1, 2 contour mesh packages together with the instruction for use are placed in a pack of cardboard.

10 ampoules together with the instructions for use are placed in a pack of cardboard with a liner of paper or corrugated ribbon, or with special nests.

Storage conditions:

In the dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 of the year.

Do not use after expiry date.

Terms of leave from pharmacies:On prescription

Registration number:LP-003595

Date of registration:04.05.2016

Expiration Date:04.05.2021

The owner of the registration certificate:TRIVIUM-XXI, LLC TRIVIUM-XXI, LLC Russia

Manufacturer: & nbsp

Armavir Biofactory, FKP

Information update date: & nbsp13.09.2017

Illustrated instructions

Instructions

Arthravir®-Inkamparm® (Artravir-Inkamfarm)