Chondroitin sulfate (Chondroitin sulfate)

Chondroitin sulfate is the main component of proteoglycans that make up the cartilaginous matrix together with collagen fibers. Has chondroprotective properties; inhibits the activity of enzymes that cause degradation of the articular cartilage; stimulates the production of proteoglycans by chondrocytes; strengthens metabolic processes in cartilage and subchondral bone; affects the phosphoric-calcium metabolism in the cartilaginous tissue, stimulates its regeneration, participates in the construction of the basic substance of bone and cartilaginous tissue. Has anti-inflammatory and analgesic properties,helps to reduce the release of inflammatory mediators and pain factors into synovial fluid through synovial and macrophage synovial membranes, suppresses the secretion of leukotriene B4 and prostaglandin E2.

The drug contributes to the restoration of the cartilaginous surfaces of the joints, prevents the collapse of connective tissue; normalizes the production of articular fluid, which leads to better mobility of joints, reducing pain intensity.