Artrum - instructions for use, dose, side effects, contraindications

Excipients: propylene glycol, ethanol (rectified ethyl alcohol), trolamine (triethanolamine thermostable), polyacrylate, rarely cross-linked (arepol), water purified to 100 g.

Description:Colorless, the gel is not greasy to the touch, with a specific smell.

Pharmacotherapeutic group:Non-steroidal anti-inflammatory drug (NSAID)

ATX: & nbsp

M.02.A.A.10 Ketoprofen

Pharmacodynamics:

Has local anti-inflammatory, antiexudative and analgesic effect, associated with inhibition of the activity of cyclooxygenases 1 and 2, regulating the synthesis of prostaglandins. In the form of a gel provides a local therapeutic effect in relation to affected joints, tendons, ligaments, muscles. With articular syndrome, weakening of pain in joints at rest and during movement, reduction of morning stiffness and swelling of the joints. Has no catabolic effect on articular cartilage.

Pharmacokinetics:

When the cutaneous application is absorbed slowly.Practically does not cumulate in the body. Bioavailability of the gel is about 5%.

Indications:

Diseases of the musculoskeletal system: rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, osteoarthrosis of the peripheral joints and spine, rheumatic soft tissue injuries.

Muscular pain of rheumatic and non-rheumatic origin.

Traumatic injuries of soft tissues without damaging the skin.

Contraindications:

Hypersensitivity to ketoprofen or other components of the drug, acetylsalicylic acid or other NSAIDs, bronchial asthma in combination with polyposis of the nasal mucosa, pregnancy (III trimester), lactation period, children's age (up to 6 years), breach of integument, dermatoses, eczema .

Carefully:

Hepatic porphyria (exacerbation), erosive and ulcerative lesions of the gastrointestinal tract, severe violations of liver and kidney function, chronic heart failure, bronchial asthma, advanced age, children under 12, pregnancy I and II trimester.

Pregnancy and lactation:

The drug should not be used in the III trimester of pregnancy.

Use in I and II trimesters is possible only after consultation with a doctor.

There is no experience of using Artrum in lactation.

Dosing and Administration:

The drug is applied externally.

One-time use 3-5 grams of the drug (the volume of a large cherry). Depending on the size of the damaged area, apply the gel 2-3 times a day or according to the prescriptions of the doctor, gently rubbing until completely absorbed.

With iontophoresis, the drug is applied to the negative pole.

The duration of treatment without consulting a doctor should not exceed 10 days.

Side effects:

Allergic reactions, photosensitivity. If any undesirable phenomenon develops, you should consult your doctor.

Overdose:

No cases of drug overdose have been reported.

Special instructions:

The drug should be applied only to intact skin. Avoid contact with eyes and mucous membranes.

To avoid manifestations of hypersensitivity and photosensitivity, it is recommended to avoid exposure to the skin of the sunlight during the course of treatment.

Form release / dosage:

Gel for external use 2.5% or 5%.

Packaging:

30 g or 50 g in aluminum tubes.

Each tube together with the instruction for use is placed in a pack of cardboard.

Storage conditions:

In a place protected from light, out of reach of children, at a temperature of no higher than 25 ° C.

Shelf life:

2 years.

Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LS-002388

Date of registration:19.01.2012

Expiration Date:Unlimited

The owner of the registration certificate:BIOSINTEZ, PAO BIOSINTEZ, PAO Russia

Manufacturer: & nbsp

BIOSINTEZ, PAO Russia

Representation: & nbspBIOSINTEZ JSC BIOSINTEZ JSC Russia

Information update date: & nbsp14.09.2017

Illustrated instructions

Instructions

Artrum (Artrum)