Side effect
The most frequent manifestations associated with the use of a cream containing ketoprofen, are local manifestations.
Classification of adverse reactions by the frequency of their detection: very often (≥1 / 10); often (≥1 / 100, <1/10); infrequently (≥1 / 1000, <1/100); rarely (≥1 / 10000, <1/1000); very rarely (<1/10000).
Allergic reactions: very rarely - angioedema, anaphylaxis.
From the skin and skin appendages: infrequently - erythema, itching, burning, eczema, transient dermatitis of mild severity; rare - hives, rashes, photosensitivity, bullous dermatitis, purpura, erythema multiforme, lichenoid dermatitis, skin necrosis, Stevens-Johnson syndrome; very rarely - a single case of severe contact dermatitis (against a background of poor hygiene and insolation), a single case of severe generalized photodermatitis, toxic epidermal necrolysis.
From the respiratory system: very rarely - asthmatic attacks as a variant of an allergic reaction.
From the urinary system: very rarely - deterioration of kidney function in patients with chronic renal failure.