From the digestive system: often - dyspepsia (nausea, diarrhea or constipation, flatulence, vomiting, heartburn, decreased appetite,) NSAID-gastropathy, abdominal pain, stomatitis, impaired liver function; rarely - perforation of the organs of the gastrointestinal tract, exacerbation of Crohn's disease, melena, gingival, gastrointestinal, hemorrhoidal bleeding.
From the central nervous system: often - headache, dizziness, insomnia, drowsiness, fatigue, agitation, nervousness, depression, asthenia; rarely - confusion or loss of consciousness, forgetfulness, migraine, peripheral neuropathy; very rarely - hallucinations, disorientation and speech disorder.
From the sense organs: rarely - noise or ringing in the ears, blurry vision, taste change, conjunctivitis, hearing loss, dry eye mucosa, eye pain, conjunctival hyperemia, vertigo.
On the part of the CAS: rarely - tachycardia, arterial hypertension, peripheral edema.
On the part of the organs of hematopoiesis: ketoprofen reduces platelet aggregation, transient increase in the level of liver enzymes, rarely - agranulocytosis, anemia, thrombocytopenia, purpura, hemolytic anemia, and leukopenia.
From the urinary system: rarely - renal dysfunction, cystitis, urethritis, interstitial nephritis, nephrotic syndrome, hematuria (often develop in people taking NSAIDs and diuretics for a long time).
Allergic reactions: often - skin reactions (itching, urticaria); rarely - rhinitis, dyspnea, bronchospasm, angioedema, anaphylactoid reactions, exfoliative dermatitis.
Other: increased sweating, rarely - hemoptysis, epistaxis, menometrorrhagia, muscle twitching, thirst, photosensitization.