Asparkam - instructions for use, dose, side effects, contraindications

Pharmacodynamics:Asparta is a source of potassium and magnesium ions, regulates metabolic processes. The mechanism of action is presumably associated with the role of aspartate as a carrier of magnesium and potassium ions in the intracellular space and with the participation of aspartate in metabolic processes. Thus, asparks eliminates the imbalance of electrolytes, reduces the excitability and conductance of the myocardium (moderate antiarrhythmic effect).

Pharmacokinetics:Easily absorbed when ingested and relatively quickly excreted by the kidneys.

Indications:

Asparks are used in complex therapy for heart failure, ischemic heart disease, hypokalemia,disorders of the heart rhythm (including with myocardial infarction, an overdose of cardiac glycosides).

Contraindications:

Hypersensitivity to the drug, an abnormality in the metabolism of amino acids, arterial hypotension, acute and chronic renal failure, hyperkalemia, hypermagnesia, violation of atrioventricular conduction (AV blockade I-III st.), Severe myasthenia gravis, acute metabolic acidosis, dehydration (exicosis), hemolysis, disease Addison.

Carefully:During pregnancy (especially the first trimester) and during lactation.

Pregnancy and lactation:Be wary appoint during pregnancy (especially the first trimester) and during lactation.

Dosing and Administration:

Aspartame is prescribed inside, after eating.

Prescribe usually adults 1-2 tablets 3 times a day. The course of treatment is 3-4 weeks. If necessary, repeat the course.

Side effects:

Possible nausea, vomiting, diarrhea, discomfort or burning sensation in the epigastric region (in patients with an anatomic gastritis or cholecystitis), atrioventricular blockade, paradoxical reaction (increase in the number of extrasystoles), hyperkalemia (nausea, vomiting, diarrhea, paresthesia), hypermagnia (red face,thirst, lowering blood pressure, hyporeflexia, respiratory depression, convulsions).

Overdose:

Symptoms: conduction disorders (especially with the previous pathology of the conduction system of the heart).

Interaction:

Pharmacodynamic: a joint application with potassium-sparing diuretics (triamterene, spironolactone), beta-adrenoblockers, cyclosporine, heparin, ACE inhibitors, non-steroidal anti-inflammatory drugs increases the risk of hyperkalemia up to the development of arrhythmia and asystole.

The use of potassium preparations together with glucocorticosteroids eliminates the hypokalemia caused by the latter. Under the influence of K +, undesirable effects of cardiac glycosides decrease.

Mg2+ reduce the effect of neomycin, polymyxin B, tetracycline and streptomycin. Anesthetics increase the oppressive effect of magnesium preparations on the central nervous system; when applied simultaneously with atrakuronium, decamethonium, succinyl chloride and suxamethonium, neuromuscular blockade may be enhanced; calcitriol increases the content of magnesium in the blood plasma; Calcium preparations reduce the effect of magnesium preparations.

Pharmacokinetic: astringent and enveloping agents reduce the absorption of the drug in the gastrointestinal tract.

Form release / dosage:Pills.

Packaging:For 10 tablets in a contour mesh, package or 50 tablets in a jar of glass with a screw mouth. Each jar or 5 contour cell packs together with the instruction is placed in a pack.

Storage conditions:

Store in a dry place at a temperature of no more than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:On prescription

Registration number:LSR-004787/07

Date of registration:13.12.2007

Expiration Date:Unlimited

The owner of the registration certificate:TATHIMFARMPREPARATY, JSC TATHIMFARMPREPARATY, JSC Russia

Manufacturer: & nbsp

TATHIMFARMPREPARATY, JSC Russia

Information update date: & nbsp27.09.2017

Illustrated instructions

Instructions

Aspark (Asparcam)