Active substancePotassium and magnesium asparaginatePotassium and magnesium asparaginate
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  • Dosage form: & nbsppills
    Composition:1 tablet contains active substances: 0.175 g of potassium aspartate and 0.175 g of magnesium aspartate, Excipients: potato starch or corn starch, talc, calcium stearate or tablet mass asparks - 0.495 g.
    Description:Tablets of white color, with a smooth surface, risk and facet, flat-cylindrical.
    Pharmacotherapeutic group:Potassium and magnesium preparation
    ATX: & nbsp

    A.12.C.X   Preparations of other minerals

    Pharmacodynamics:Asparta is a source of potassium and magnesium ions, regulates metabolic processes. The mechanism of action is presumably associated with the role of aspartate as a carrier of magnesium and potassium ions in the intracellular space and with the participation of aspartate in metabolic processes. Thus, asparks eliminates the imbalance of electrolytes, reduces the excitability and conductance of the myocardium (moderate antiarrhythmic effect).
    Pharmacokinetics:Easily absorbed when ingested and relatively quickly excreted by the kidneys.
    Indications:

    Asparks are used in complex therapy for heart failure, coronary heart disease, hypokalemia, heart rhythm disturbances (including, with myocardial infarction, cardiac glycosides overdose).

    Contraindications:

    Hypersensitivity to the drug (including sorbitol and fructose), impaired metabolism of amino acids, arterial hypotension, acute and chronic renal insufficiency, hyperkalemia, hypermagnia, violation of atrioventricular conduction (AV blockade I-III st.), severe myasthenia gravis, acute metabolic acidosis, impaired metabolism of amino acids, arterial hypotension, dehydration (exicosis), hemolysis, Addison's disease.

    Carefully:During pregnancy (especially the first trimester) and during lactation.
    Pregnancy and lactation:

    Be wary appoint during pregnancy (especially the first trimester) and during lactation.

    Dosing and Administration:

    Aspartame is prescribed inside, after eating.

    Prescribe usually adults 1-2 tablets 3 times a day. The course of treatment is 3-4 weeks. If necessary, repeat the course.

    Side effects:

    There may be nausea, vomiting, diarrhea,unpleasant sensations or burning sensation in the epigastric region (in patients with an anatomic gastritis or cholecystitis), atrioventricular blockade, paradoxical reaction (increase in the number of extrasystoles). K + salts: paresthesia, lowering blood pressure, phlebitis, vein thrombosis; hyperkalemia; dyspnea; diarrhea, nausea, vomiting; abdominal pain, ulceration of the mucous membrane of the gastrointestinal tract, bleeding from the digestive tract, flatulence; muscle weakness; itching.

    Salt Mg2+: fatigue, hyporeflexia; dizziness; decrease in blood pressure, bradycardia; dyspnea; diarrhea, dry mouth, nausea; hyperhidrosis, sweating.

    Overdose:

    Symptoms: conduction disorders (especially with the previous pathology of the conduction system of the heart).

    Interaction:

    Pharmacodynamic: the combined use of potassium preparations with disopyramide or quinidine increases the undesirable effect of the latter on the cardiovascular system. The combined use of potassium-sparing diuretics (triamterene, spironolactone) increases the risk of hyperkalemia up to arrhythmia and cardiac arrest.

    The use of potassium preparations in conjunction with glucocorticosteroids eliminates hypokalemia,called by the latter. Under the influence of potassium preparations, undesirable effects of cardiac glycosides decrease.

    Pharmacokinetic: binders and coating agents reduce absorption of the drug in the gastrointestinal tract.

    Special instructions:

    It is necessary to constantly monitor the potassium content in the blood plasma (for example, according to the electrocardiogram).

    Form release / dosage:

    Pills.

    Packaging:10 or 50 tablets in a planar cell pack.
    Storage conditions:

    Store in a dry place at a temperature of 10 to 40 ° C. Keep out of the reach of children.

    Shelf life:3 years. Do not use after the date shown on the package.
    Terms of leave from pharmacies:On prescription
    Registration number:P N014654 / 01-2003
    Date of registration:12.12.2008
    Expiration Date:Unlimited
    The owner of the registration certificate:LUHANSKY HFZ, OJSC LUHANSKY HFZ, OJSC Ukraine
    Manufacturer: & nbsp
    Information update date: & nbsp27.09.2017
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