Asparkam - instructions for use, dose, side effects, contraindications

Asparkam tablet mass derived from active substances: magnesium aspartate tetrahydrate, potassium asparaginate hemihydrate; auxiliary substances: potato starch, talc, which corresponds to magnesium asparaginate tetrahydrate 175 mg, potassium asparaginate hemihydrate 175 mg,

Excipients: calcium stearate monohydrate, copovidone (Kollidon VA-64).

Description:Tablets are white or almost white in color, flat-cylindrical, with a risk and a facet.

Pharmacotherapeutic group:Potassium and magnesium preparation

ATX: & nbsp

A.12.C.X Preparations of other minerals

Pharmacodynamics:Asparta is a source of potassium and magnesium ions, regulates metabolic processes. The mechanism of action is presumably associated with the role of aspartate as a carrier of magnesium and potassium ions in the intracellular space and with the participation of aspartate in metabolic processes. Thus, asparks eliminates the imbalance of electrolytes, reduces the excitability and conductance of the myocardium (moderate antiarrhythmic effect).

Pharmacokinetics:Easily absorbed when ingested and relatively quickly excreted by the kidneys.

Indications:Aspartame is used in complex therapy for heart failure, coronary heart disease, hypokalemia, heart rhythm disturbances (including myocardial infarction, cardiac glycoside overdose).

Contraindications:Hypersensitivity to the drug, the loss of amino acid metabolism, arterial hypotension, acute and chronic renal failure, hyperkalemia, hypermagnesia, violation of atrioventricular conduction (AV I-III degree), severe myasthenia gravis, acute metabolic acidosis, dehydration (exicosis), hemolysis, Addison's disease, oliguria, anuria.

Carefully:Pregnancy (especially I trimester), lactation period, hypophosphatemia, urolithic diathesis (associated with impaired calcium, magnesium and ammonium phosphate exchange).

Dosing and Administration:

Asparkam is prescribed inside after eating.

Prescribe usually adults 1-2 tablets 3 times a day. The course of treatment is 3-4 weeks. If necessary, repeat the course.

Side effects:Possible nausea, vomiting, diarrhea, discomfort or burning sensation in the pancreas (in patients with an anatomic gastritis or cholecystitis), atrioventricular blockade,paradoxical reaction (increase in the number of extrasystoles), hyperkalemia (nausea, vomiting, diarrhea, parasthesia), hypermagnesia (facial flushing, thirst, lowering of blood pressure, hyporeflexia, respiratory depression, convulsions).

Overdose:

Symptoms: hyperkalemia, hypermagnia.

Treatment: symptomatic.

Interaction:

Pharmacodynamic: a joint application with potassium-sparing diuretics (triamterene, spironolactone), beta-adrenoblockers, cyclosporine, heparin, angiotensin converting enzyme (ACE) inhibitors, non-steroidal anti-inflammatory drugs increases the risk of hyperkalemia up to the development of arrhythmia and asystole. The use of potassium preparations together with glucocorticosteroids eliminates the hypokalemia caused by the latter. Under the influence of potassium, undesirable effects of cardiac glycosides decrease. Magnesium reduces the effect of neomycin, polymyxin B, tetracycline and streptomycin. Anesthetics increase the oppressive effect of magnesium preparations on the central nervous system; when applied simultaneously with atrakuronium, decamethonium,succinyl chloride and suxamethonium may enhance neuromuscular blockade; calcitriol increases the content of magnesium in blood plasma, calcium preparations reduce the effect of magnesium preparations.

Strengthens the negative dromo- and batmotropic effect of antiarrhythmic drugs.

Pharmacokinetic: astringent and enveloping agents reduce the absorption of the drug in the gastrointestinal tract.

Form release / dosage:Pills.

Packaging:10 tablets per contour cell or cell-free packaging. For 2 or 3 contour packagings along with the instructions for use are placed in a pack. It is allowed to use contoured cell packs with an equal number of instructions for use in a carton box box. Contour non-cellular packages with an equal number of instructions for use are placed in a carton box box.

Storage conditions:

In a dry place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:3 years. The drug can not be used after the expiration date.

Terms of leave from pharmacies:On prescription

Registration number:LSR-000025

Date of registration:29.03.2007 / 25.12.2009

Expiration Date:Unlimited

The owner of the registration certificate:MARBIOFARM, OJSC MARBIOFARM, OJSC Russia

Manufacturer: & nbsp

MARBIOFARM, OJSC Russia

Information update date: & nbsp27.09.2017

Illustrated instructions

Instructions

Aspark (Asparcam)