Berrocca Plus - instructions for use, dose, side effects, contraindications

active ingredients: thiamine mononitrate (vitamin B₁) 15 mg, riboflavin (vitamin B₂) 15 mg, nicotinamide (vitamin AT₃) 50 mg, calcium pantothenate (vitamin B₅) 23 mg, piridoxine hydrochloride (vitamin B₆) 10 mg, bIotine (vitamin B₈) 0.15 mg, folic acid (vitamin B₉) 0.4 mg, qand an anocobalamin (vitamin B₁₂) 0.01 mg, andscorbic acid (vitamin C) 500 mg, calcium (in the form of calcium carbonate and calcium pantothenate) 100 mg, magnesium (in the form of magnesium hydroxycarbonate and magnesium oxide of the lung) 100 mg, zinc (in the form of zinc citrate trihydrate) 10 mg;

Excipients: lactose monohydrate 94.3 mg, povidone K 90 (E 1201) 45 mg, croscarmellose sodium (E 468) 44 mg, mannitol (E 421) 25.45 mg, talc (E 553b) 15 mg, magnesium stearate (E 572) 14 mg;

shell: opaque brown 43 mg: polydextrose (E 1200), hypromellose (E 464), titanium dioxide (E 171), coconut oil fractionated, iron oxide pigment yellow (E 172), iron oxide dye red (E 172), iron oxide dye black (E 172).

Description:

Oblong biconvex tablets covered with a film membrane, from pale orange to grayish-orange color.

Pharmacotherapeutic group:Multivitamin Means + Minerals

ATX: & nbsp

A.11.A.A.04 Multivitamins and microelements

Pharmacodynamics:

Combined drug, the pharmacological action of which is due to its constituent complex of vitamins and trace elements.

Vitamins of group B participate in many metabolic reactions, including the synthesis of neurotransmitters.

Vitamin C (ascorbic acid) is a biological antioxidant and plays an important role in the inactivation of free radicals, increases the absorption of iron in the small intestine, affects the metabolism of folic acid and the function of leukocytes. Stimulates the formation of connective tissue, bone tissue, normalizes the permeability of capillaries.

Calcium takes part in many physiological processes, enzyme systems and transmission of a nerve impulse in combination with magnesium and vitamin B₆.

Magnesium participates in various reactions, including protein synthesis, fatty acid metabolism, oxidation of sugars.

Zinc as a catalyst activates more than 200 enzymes and is a component of many proteins, hormones, neuropeptides, hormonal receptors, and also directly participates in the synthesis of coenzymes, derivatives of vitamin B₆.

Water-soluble vitamins do not accumulate in the body, so when conditions are accompanied by an increased need for vitamins and minerals, the amount of vitamins that come with food may not be sufficient.

Indications:

Deficiency or condition, accompanied by an increased need for vitamin B, vitamin C and zinc.

The content of vitamins in the Berroca® Plus preparation is selected for therapeutic use and is used for conditions accompanied by a deficiency or increased demand for vitamins (increased physical exertion, prolonged nervous stress and stress, inadequate and unbalanced diet (restrictive diets), chronic alcoholism.

Contraindications:

Hypersensitivity to the drug components, hypercalcemia, hypermagnesia, urolithiasis (nephrolithiasis, urolithiasis), hemochromatosis, hyperoxaluria, impaired renal function, deficiency of glucose-6-phosphate dehydrogenase, children under 15 years.

Carefully:

At an atrophic gastritis, diseases of the intestine, pancreas, with a syndrome of insufficiency of absorption of vitamin B₁₂ or a congenital deficiency of Castle's internal factor.

Pregnancy and lactation:

Berokka® Plus is not suitable for use in pregnant or lactating women.Vitamins and minerals in doses used in food additives are generally considered safe for use during pregnancy and lactation. However, the Berrock® Plus preparation should be used during pregnancy only as directed by your doctor.

The vitamins and minerals contained in the Berroca® Plus preparation penetrate into breast milk. Data on the safety of the drug when used during lactation there.

Dosing and Administration:

The drug is taken orally with water.

Adults and children from the age of 15: 1 tablet per day.

Do not exceed the recommended daily dose of the drug.

The recommended course duration is 30 days. Repeated courses on the recommendation of a doctor.

Side effects:

Allergic reactions: possible hives, rash, swelling of the larynx, anaphylactic shock.

Digestive system: possible mild transient gastrointestinal disorders.

Blood and hematopoiesis system: in patients with deficiency of glucose-6-phosphate dehydrogenase ascorbic acid can cause hemolytic anemia.

Nervous system: possible headache, dizziness, insomnia, excitability.

Overdose:

Symptoms of overdose may include gastrointestinal disorders, such as diarrhea and a feeling of discomfort in the stomach. Excessive intake of vitamin A AT₆ (more than 20 tablets per day and for several months) can lead to symptoms of neuropathy.

In case of an overdose, stop taking the drug and consult a doctor.

Interaction:

Vitamin B₆ (pyridoxine), in a dose exceeding 5 mg, can neutralize the effect of levodopa in patients with Parkinsonism. However, such antagonism is not observed if levodopa It is used in combination with a decarboxylase inhibitor (eg, benserazide, carbidopa).

Thiosemicarbazone and 5-fluorouracil neutralize the action of vitamin B₁. Antacid preparations inhibit the resorption of vitamin B₁.

Neomycin, aminosalicylic acid and H₂-blockers reduce the absorption of vitamin B₁₂.

Oral contraceptives can reduce serum vitamin levels AT₁₂, folic acid, pyridoxine, ascorbic acid.

Some patients who receive daily deferoxamine and vitamin C in a dose of 500 mg, transient disturbances of left ventricular function may be noted.

Special instructions:

Vitamin C can affect the results of the test to determine glucose in the urine, despite the fact that it does not affect the blood sugar level. The intake of vitamin C should be discontinued a few days before such tests.

It is possible to stain urine in a bright yellow color, which is not clinically significant and is explained by the presence of riboflavin in the preparation.

The preparation does not contain fat-soluble vitamins. One tablet contains the maximum daily dose of vitamin B₆ (pyridoxine), therefore, do not exceed recommended doses.

One tablet contains 12.5% of the recommended daily intake of calcium and 33.3% of the recommended daily intake of magnesium. However, for the treatment of calcium and magnesium deficiency, taking only Berrock® Plus is not sufficient.

Information for patients with diabetes mellitus. One tablet contains 25 mg of mannitol, 94 mg of lactose monohydrate and 13.44 mg of dextrose, which corresponds to 0.02 breadsdinitsa (XE) and energy value of 0.143 kcal, so the drug can be taken in patients with diabetes mellitus.

Patients taking other medicines,should consult with your doctor before starting Berokka® Plus.

Effect on the ability to drive transp. cf. and fur:

Has little or no effect on the ability to drive or drive machinery.

Form release / dosage:Film-coated tablets.

Packaging:

For 10 or 20 tablets coated with a film sheath in PVC / PE / PVDC / Al blister.

For 3, 6 or 10 blisters (10 tablets) or 3, 5 blisters (20 tablets each) together with instructions for use in a cardboard pack.

Storage conditions:

At a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:LS-001921

Date of registration:24.08.2010 / 11.10.2016

Expiration Date:Unlimited

The owner of the registration certificate:BAYER, AO BAYER, AO Russia

Manufacturer: & nbsp

BAYER, CJSC Russia

Representation: & nbspBAYER, AOBAYER, AO

Information update date: & nbsp23.01.2017

Illustrated instructions

Instructions

Berroca® Plus (Berocca® plus)