Active substanceMultivitamins + MineralsMultivitamins + Minerals
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  • Dosage form: & nbsptablets, effervescent
    Composition:

    1 tablet contains:

    active ingredients: vitamin B1 (thiamine hydrochloride)1 15 mg, vitamin B2 (riboflavin) 15 mg, vitamin B6 (pyridoxine hydrochloride) 10 mg, vitamin B12 (cyanocobalamin)3 0.01 mg, vitamin B3 (nicotinamide) 50 mg, vitamin B5 (pantothenic acid)4 23 mg, biotin 0.15 mg, folic acid 0.4 mg, vitamin C (ascorbic acid) 500 mg, calcium (in the form of calcium carbonate and calcium pantothenate)5 100 mg, magnesium (in the form of magnesium carbonate, heavy and magnesium sulfate dihydrate)6 100 mg, zinc (in the form of zinc trihydrate)7 10 mg;

    Excipients: citric acid, anhydrous 1700 mg sodium bicarbonate 840 mg, sodium carbonate, anhydrous 60 mg Sodium chloride 40 mg, potassium acesulfame 20 mg, aspartame 25 mg, beetroot red (E162) 30 mg, beta-carotene (E160a) 40 mg orange flavor 100 mg, polysorbate 60 0.9 mg, mannitol 16.848 mg, isomalt 265.531 mg, sorbitol 155.3027 mg.

    1in the form of thiamine monophosphoric acid ester chloride 18.54 mg.

    2in the form of riboflavin sodium phosphate 20.51 mg.

    Зin the form of cyanocobalamin 0.1% 10.0 mg.

    4in the form of calcium pantothenate 25 mg.

    5in the form of calcium carbonate granular (calcium carbonate and maltodextrin) 97.69 mg and calcium pantothenate 2.31 mg.

    6magnesium carbonate in granular form (heavy magnesium carbonate and pregelatinized corn starch) 49.0 mg of magnesium sulfate dihydrate and 51.0 mg.

    7in the form of zinc citrate trihydrate.

    Description:Ploskotsilindrichesky tablets from pale orange to light orange color, with impregnations of more dark and more light color,dissolve in water with the release of bubbles, forming a solution with the smell of orange.
    Pharmacotherapeutic group:multivitamin agent + minerals
    ATX: & nbsp

    A.11.A.A.04   Multivitamins and microelements

    Pharmacodynamics:

    Combined drug, the pharmacological action of which is due to its constituent complex of vitamins and trace elements.

    Vitamins of group B participate in many metabolic reactions, including the synthesis of neurotransmitters.

    Vitamin C (ascorbic acid) is a biological antioxidant and plays an important role in the inactivation of free radicals, increases the absorption of iron in the small intestine, affects the metabolism of folic acid and the function of leukocytes. Stimulates the formation of connective tissue, bone tissue, normalizes the permeability of capillaries.

    Calcium takes part in many physiological processes, enzyme systems and transmission of a nerve impulse in combination with magnesium and vitamin B6.

    Magnesium participates in various reactions, including protein synthesis, fatty acid metabolism, oxidation of sugars.

    Zinc as a catalyst activates more than 200 enzymes and is a componentmany proteins, hormones, neuropeptides, hormonal receptors, and also directly participates in the synthesis of coenzymes, derivatives of vitamin B6.

    The content of vitamins in the Berroca® Plus preparation is selected for therapeutic use and is used for conditions accompanied by a deficiency or increase in the need for vitamins (increased physical exertion, prolonged nervous stress and stress, inadequate and unbalanced diet (restricting diets), in the elderly people with chronic alcoholism, nicotine addiction (y smokers), as well as when using oral contraceptives in women).

    Water-soluble vitamins do not accumulate in the body, so when conditions are accompanied by an increased need for vitamins and minerals, the amount of vitamins that come with food may not be sufficient.

    Indications:

    Deficiency or conditions, accompanied by an increased need for vitamin B, vitamin C and zinc.

    Contraindications:

    Hypersensitivity to the drug components, hypercalcemia, hypermagnesia, urolithiasis (nephrolithiasis, urolithiasis), hemochromatosis, hyperoxaluria,impaired renal function, glucose-6-phosphate dehydrogenase deficiency, fructose intolerance, children under 15 years of age.

    Carefully:

    With atrophic gastritis, intestinal diseases, pancreas, with a syndrome of insufficiency of absorption of vitamin AT12 or a congenital deficiency of Castle's internal factor.

    Pregnancy and lactation:

    When using the drug Berroka® Plus in the recommended dosage of data on the negative effect of the drug on the course of pregnancy or the health of the child is not revealed. However, during pregnancy, the drug should be taken strictly for medical reasons.

    The vitamins and minerals contained in the Berroca® Plus preparation penetrate into breast milk. Data on the safety of the drug when used during lactation there.

    Dosing and Administration:

    The drug is taken orally by first dissolving the tablet in a glass of water.

    Adults and children from the age of 15: 1 tablet per day.

    Do not exceed the recommended daily dose of the drug.

    The recommended duration of treatment is 30 days.

    Repeated courses on the recommendation of a doctor.

    Side effects:

    Allergic reactions: rarely (<1/10000) urticaria, rash, laryngeal edema, anaphylactic shock.

    Digestive system: possible mild transient gastrointestinal disorders.

    Blood and hematopoiesis system: in patients with deficiency of glucose-6-phosphate dehydrogenase ascorbic acid can cause hemolytic anemia.

    Nervous system: headache, dizziness, insomnia, excitability.

    Overdose:

    There were no cases of overdose.

    Overdose Symptoms may include gastrointestinal disorders, such as diarrhea and a feeling of discomfort in the stomach. Excessive intake of vitamin B6 (more than 20 tablets per day and for several months) can lead to symptoms of neuropathy.

    In case of an overdose, stop taking the drug and consult a doctor.

    Interaction:

    Vitamin B6 (pyridoxine), in a dose exceeding 5 mg, can neutralize the effect of levodopa in patients with Parkinsonism. However, this antagonism is not observed if levodopa It is used in combination with a decarboxylase inhibitor (eg, benserazide, carbidopa).

    Thiosemicarbazone and 5-fluorouracil neutralize the action of vitamin B1.

    Antacid preparations inhibit the resorption of vitamin B1.

    Neomycin, aminosalicylic acid and H2-blockers reduce the absorption of vitamin B12.

    Aspirin reduces the absorption of ascorbic acid by about a third.

    Oral contraceptives can reduce serum levels of vitamin B12, folic acid, pyridoxine, ascorbic acid.

    Some patients who receive daily deferoxamine and vitamin C in a dose of 500 mg, transient disturbances of left ventricular function may be noted.

    Special instructions:

    Vitamin C can affect the results of the test to determine glucose in the urine, despite the fact that it does not affect the blood sugar level. The intake of vitamin C should be discontinued a few days before such tests.

    It is possible to stain urine yellow, which is not clinically significant and is explained by the presence of riboflavin in the preparation.

    The preparation does not contain fat-soluble vitamins.

    One tablet contains the maximum daily dose of vitamin B6 (pyridoxine), therefore, do not exceed recommended doses.

    One tablet contains 12.5% ​​recommendedbath daily intake of calcium and 33.3% of the recommended daily intake of magnesium. However, for the treatment of calcium and magnesium deficiency, taking only Berrock® Plus is not sufficient.

    One tablet contains 272 mg of sodium, so patients who observe a low-salt diet, it is recommended to take the drug Berroka® Plus in the form of coated tablets.

    Information for patients with diabetes mellitus. In one tablet of the drug contains 276 mg of mannitol, which corresponds to 0,028 units of bread (ХЕ) and energy value of 0,66 kcal, so the drug can be taken in patients with diabetes mellitus. If you have intolerance to some sugars before taking the drug, you should consult your doctor.

    Patients taking other medications should consult a physician before starting Berokka® Plus.

    Effect on the ability to drive transp. cf. and fur:Does not affect.
    Form release / dosage:The tablets are effervescent.
    Packaging:

    For 10 or 15 effervescent tablets wrapped in foil, in an aluminum or polypropylene cylinder, closed with a plastic lid with the control of the first opening. A desiccant is placed in the cover.

    For 1 or 2 cylinders (10 tablets) or 1, 2 or 3 cylinders (15 tablets each) together with instructions for use in a cardboard box.

    Storage conditions:

    At a temperature of no higher than 25 ° C, in a tightly closed container.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after expiry date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LS-001948
    Date of registration:27.08.2010
    The owner of the registration certificate:BAYER, AO BAYER, AO Russia
    Manufacturer: & nbsp
    Representation: & nbspBAYER, AOBAYER, AO
    Information update date: & nbsp21.08.2015
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