Bilobyl intens 120 - instructions for use, dose, side effects, contraindications

Lactose monohydrate 198.00 mg, starch corn 90.00 mg, talc 24.00 mg, silicon dioxide colloid 6.00 mg, magnesium stearate 6.00 mg, dextrose liquid [dextrose, oligo and polysaccharides] 6.00 mg

Composition of hard gelatin capsule (body and lid):

(E172) 0.1000%, iron dye oxide red (E172) 0.6000%, titanium dioxide (E171) 1.3300%, iron dye oxide yellow (E172) 0.2700%, gelatin to 100%

* Ginkgo bilobate leaf extract is dry from Ginkgo bilabial leaf (Ginkgo biloba L., Ginkgoaceae family (Ginkgoaceae), folium).

The ratio of the amount of medicinal plant material to the amount of the initial extract: 35 - 67: 1.

Extractant - acetone / water.

Description:

Hard gelatin capsules No. 0, body and cap of brown color. The contents of the capsules are powder from light brown to dark brown with particles of a darker color. Presence of lumps is allowed.

Pharmacotherapeutic group:Angioprotective agent of plant origin

ATX: & nbsp

N.06.D.X.02 Ginkgo Biloba Leaf Extract

Pharmacodynamics:

The preparation Bilobil® intens 120 is of vegetable origin. Increases the body's resistance to hypoxia, especially brain tissue, inhibits the development of traumatic or toxic edema of the brain, improves cerebral and peripheral blood circulation, improves blood rheology. Has a dose-dependent regulatory effect on the vascular wall, dilates the small arteries, increases the tone of the veins. Prevents formation of free radicals and peroxide oxidation of cell membrane lipids.Normalizes the release, reabsorption and catabolism of neurotransmitters (norepinephrine, dopamine, acetylcholine) and their ability to combine with receptors. It improves the metabolism in organs and tissues, promotes the accumulation of macroerges in cells, increases utilization of oxygen and glucose, normalization of mediator processes in the central nervous system.

Indications:

Dyscirculatory encephalopathy of various etiologies (developing as a result of stroke, craniocerebral trauma, in old age), accompanied by: decreased attention, weakened memory, decreased intellectual abilities, sleep disturbance;
violation of peripheral circulation and microcirculation (including arteriopathy of the lower extremities, intermittent claudication), Raynaud's syndrome;
neurosensory disorders (dizziness, ringing in the ears, hypoacusia);
senile macular degeneration;
diabetic retinopathy.

Contraindications:

Hypersensitivity to the extract of ginkgo or other components of the drug;
children's age till 18 years;
decreased blood clotting;
erosive gastritis;
peptic ulcer of the stomach and duodenum in the stage of exacerbation; acute disturbance of cerebral circulation;
pregnancy;
the period of breastfeeding;
acute myocardial infarction;
Galactosemia, lactase deficiency, glucose-galactose malabsorption syndrome, as. the composition of the preparation Bilobil® intens 120 includes lactose.

Pregnancy and lactation:

The preparation Bilobil® intens 120 is not recommended during pregnancy and during breast-feeding, due to the lack of sufficient experience of use.

Dosing and Administration:

Inside, 1 capsule 1-2 times a day. Capsules should be swallowed whole, washed down with a small amount of water, regardless of food intake.

With a double dose regimen to take in the morning and in the evening, with a single dose - preferably in the morning.

The course of treatment is not less than 3 months. The first signs of improvement usually appear after 1 month. Conducting a second course is possible after consulting a doctor.

Side effects:

Classification of the frequency of development of side effects of the World Organization

Health (WHO):

very often> 1/10

often from> 1/100 to <1/10

infrequently from> 1/1000 to <1/100

In each group, undesirable effects are presented in order of decreasing severity.

From the digestive system: very rarely - nausea, vomiting, diarrhea.

From the nervous system: very rarely - headache, dizziness, insomnia.

From the side of the hemostasis system: very rarely - a decrease in blood clotting, bleeding (with prolonged use in patients who simultaneously took drugs reducing blood clotting).

Allergic reactions: very rarely - redness of the skin, swelling, itching.

Other: very rarely - hearing impairment.

In case of occurrence of any undesirable phenomena, the drug should be discontinued and consulted by the treating doctor.

Overdose:

At present, no cases of overdose of Bilobyl® intens 120 have been reported.

Interaction:

It is not recommended to use the drug for patients who constantly take drugs that reduce blood clotting (for example, anticoagulants (direct and indirect action), acetylsalicylic acid and other non-steroidal anti-inflammatory drugs). Simultaneous use with these drugs may increase the risk of bleeding due to prolonged coagulation time.

Special instructions:

When developing a hypersensitivity reaction, the drug should be discontinued. Before surgery, it is necessary to inform the doctor about the use of Bilobyl® intens 120.

When there is repeated dizziness and noise in the ears, you should see a doctor. In case of sudden deterioration or loss of hearing, you should immediately consult a doctor.

Patients with bleeding (hemorrhagic diathesis) and patients receiving anticoagulant therapy should consult with a physician before starting therapy with Bilobyl® intens 120.

Effect on the ability to drive transp. cf. and fur:

During the period of taking the drug, care should be taken when carrying out potentially hazardous activities requiring increased concentration of attention and speed of psychomotor reactions (including: control of vehicles, work with moving mechanisms).

Form release / dosage:

Capsules, 120 mg.

Packaging:

10 capsules per blister (contour mesh packaging) made of a combined material PVC / PVDC and aluminum foil.

For 2 or 6 blisters (contour mesh packages), together with instructions for use, put in a cardboard pack.

Storage conditions:

At a temperature of no higher than 25 ° C, in the original packaging.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use the drug after the expiration date.

Terms of leave from pharmacies:On prescription

Registration number:LP-002056

Date of registration:18.04.2013 / 17.10.2013

Expiration Date:18.04.2018

The owner of the registration certificate:KRKA, dd, Novo mesto, AOKRKA, dd, Novo mesto, AO

Manufacturer: & nbsp

KRKA, dd, Novo mesto, AO Slovenia

KRKA-RUS, LLC Russia

Representation: & nbspKRKA, dd, Novo mesto, AOKRKA, dd, Novo mesto, AO

Information update date: & nbsp25.01.2017

Illustrated instructions

Instructions

Bilobil® intens 120 (Bilobil® intans 120)