Dexpanthenol - instructions for use, dose, side effects, contraindications

Excipients: paraffin white soft (petrolatum white, petrolatum) 270.0 mg; Lanolin (lanolin anhydrous) 170.0 mg; paraffin liquid (mineral oil, vaseline oil) 100.0 mg; isopropyl myristate 30.0 mg; cholesterol (cholesterol) 5.0 mg; methylparahydroxybenzoate (methylparaben, nipagin) 0.7 mg; propyl parahydroxybenzoate (propylparaben, pipazole) 0.3 mg; water purified to 1.0 g.

Description:

Homogeneous ointment light yellow color from characteristic smell of lanolin.

Pharmacotherapeutic group:Reparation of tissue stimulant

ATX: & nbsp

D.03.A.X.03 Dexpanthenol

S.01.X.A.12 Dexpanthenol

D.03.A.X Other drugs that promote normal scarring

S.01.X.A Other drugs for the treatment of eye diseases

Pharmacodynamics:Dexpanthenol is a derivative of pantothenic acid. Pantothenic acid is a water-soluble vitamin B (vitamin B₅) - is an integral part of coenzyme A. Stimulates skin regeneration, normalizes cellular metabolism, increases the strength of collagen fibers. The increase in the demand for pantothenic acid is observed when the skin or tissues are damaged, and its deficiency can be compensated by topical application of dexpanthenol.Optimum molecular weight, hydrophilicity and low polarity make it possible to penetrate all layers of the skin. It has a regenerating, weak anti-inflammatory effect.

Pharmacokinetics:

Suction, distribution

When applied externally, it is rapidly absorbed and converted into pantothenic acid, binds to blood plasma proteins (mainly with beta-globulin and albumin). The concentration of pantothenic acid in the blood is 0.5-1 mg / l, in blood plasma - 100 μg / l.

Metabolism, excretion

Pantothenic acid is not metabolized in the body and is excreted unchanged by the kidneys.

Indications:

- Violations of the integrity of the skin, caused by mechanical, chemical, temperature factors or after surgical interventions:

burns of different origin (including solar ones);
scratches, abrasions, wounds, sores;
poorly healing skin grafts;
aseptic postoperative frames;

- inflammatory processes on the skin: dermatitis, furuncles, trophic ulcers of the lower extremities;

- care of the skin around the tracheostist, gastrostom and colostrum;

- treatment and prevention of the effects of adverse effects on the skin of environmental factors (cold, wind, dampness);

- in children: diaper dermatitis, skin irritation, treatment and prevention of diaper rash;

- in nursing mothers: cracks and inflammation of the nipples of the breast;

- treatment and protection of dry skin as a source of neutral fats and dexpanthenol.

Contraindications:

Hypersensitivity to any of the components of the drug.

Pregnancy and lactation:

A drug Dexpanthenol can be used during pregnancy and during breastfeeding.

Dosing and Administration:

Outwardly.

Ointment is applied 2-4 times a day (if necessary more often).

Apply a thin layer on the affected area of the skin, lightly rubbing. In case of application on the infected skin surface, it should be pretreated with any antiseptic.

Breastfeeding mothers lubricate the surface of the nipple with ointment after each breast-feeding.

Breast children are given ointment after each change of underwear or water treatment.

The duration of the drug and the possibility of a repeat course of treatment depend on the individual characteristics of the course of the disease in the patient, and are determined by the therapeutic effect achieved and the tolerability of the drug.

Side effects:

Allergic reactions (including slowed down due to the presence of parahydroxybenzoates in the drug) - hives, itching.

If any of the side effects listed in the manual are aggravated or any other side effects not indicated in the instructions are noted, the doctor should be informed immediately.

Overdose:

No cases of overdose have been reported.

Interaction:Cases of interaction with other medicinal products for external use are unknown.

Special instructions:

Treatment of trophic ulcers and poorly healing skin grafts should be performed under the supervision of the attending physician.

Do not apply to dying wounds.

Avoid contact with eyes.

Effect on the ability to drive transp. cf. and fur:

A drug Dexpanthenol does not affect the ability to drive vehicles and mechanisms.

Form release / dosage:

Ointment for external use, 5%.

Packaging:

30 g or 100 g in an aluminum tube.

Each tube together with the instruction for use is placed in a pack of cardboard.

Storage conditions:

Store at a temperature not exceeding 25 ° C.

Keep out of the reach of children.

Shelf life:

2 years.

Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-000293/08

Date of registration:04.02.2008 / 25.08.2016

Expiration Date:Unlimited

The owner of the registration certificate:VERTEKS, AO VERTEKS, AO Russia

Manufacturer: & nbsp

VERTEKS, AO Russia

Representation: & nbspVERTEKS CJSC VERTEKS CJSC Russia

Information update date: & nbsp22.03.2017

Illustrated instructions

Instructions

Dexpanthenol (Dexpanthenol)