D-Panthenol - instructions for use, dose, side effects, contraindications

Excipients: Vaseline 27.00 g; paraffin liquid 10.00 g; lanolin 17.00 g; cholesterol 0.50 g; isopropyl myristate 3.00 g; methyl parahydroxybenzoate 0.07 g; propyl parahydroxybenzoate 0.03 g; water 37.40 g.

Description:

Homogeneous ointment from white with a yellowish tinge to light yellow color, with a specific smell.

Pharmacotherapeutic group:tissue repair stimulant

ATX: & nbsp

D.03.A.X.03 Dexpanthenol

S.01.X.A.12 Dexpanthenol

D.03.A.X Other drugs that promote normal scarring

S.01.X.A Other drugs for the treatment of eye diseases

Pharmacodynamics:

Dexpanthenol is a derivative of pantothenic acid. Pantothenic acid - water-soluble vitamin B (vitamin B5) - is an integral part of coenzyme A (Co-A). Stimulates skin regeneration, normalizes cellular metabolism, increases the strength of collagen fibers. The increase in the demand for pantothenic acid is observed when the skin or tissues are damaged, and its deficiency can be compensated for by external application of dexpanthenol. Optimum molecular weight, hydrophilicity and low polarity make it possible penetration into all layers of the skin.Has a weak anti-inflammatory effect.

Pharmacokinetics:

When topical application is rapidly absorbed and converted to pantothenic acid, binds to plasma proteins (mainly with beta-globulin and albumin).

Its concentration in the blood is 0.5-1 mg / l, in the blood serum - 100 μg / l. Pantothenic acid is not metabolized (except for inclusion in Co-A), is excreted unchanged by the kidneys.

Indications:

Violations of the integrity of the skin, caused by mechanical, chemical, temperature factors or after surgical interventions:

- burns of different origin (including solar ones);

- scratches, abrasions, wounds, sores;

- poorly healing skin grafts, aseptic postoperative wounds;

- inflammatory processes on the skin: dermatitis, furuncle, trophic ulcers of the lower extremities;

- care for the skin around the tracheostist, gastrostom and colostrum;

- treatment and prevention of the effects of adverse effects on the skin of environmental factors (cold, wind, dampness).

Children: diaper dermatitis, skin irritation, treatment and prevention of diaper rash. Cracks and inflammations of the nipples of the breast in nursing mothers.

It is also used for the treatment and protection of dry skin, as a source of neutral fats and dexpanthenol.

Contraindications:

D-Panthenol ointment should not be used if hypersensitivity to the components of the drug.

Pregnancy and lactation:

D-Panthenol Ointment can be used during pregnancy and during breastfeeding.

Dosing and Administration:

Outwardly.

Ointment is applied 2-4 times a day (if necessary more often), a thin layer on the affected skin area, lightly rubbing. In the case of infliction on theirradiateda surface of the skin, it should be pretreated with any antiseptic.

Breastfeeding mothers It is necessary to lubricate the surface of the nipple with ointment after each breast-feeding.

Breast children (including newborns) are given ointment after each change of clothes or water procedure.

The duration of the drug and the possibility of a repeat course of treatment depend on the individual characteristics of the course of the disease in the patient, and is determined by the therapeutic effect achieved and the tolerability of the drug.

Side effects:

Allergic reactions (including delayed due to the presence of parahydroxybenzoates in the formulation).

If any of the side effects indicated in the manual are aggravated or you notice any other side effects not listed in the instructions, inform your doctor.

Overdose:

No cases of overdose have been reported.

Interaction:

The interaction of dexpanthenol with other drugs for external use is not established.

Special instructions:

Treatment of trophic ulcers and poorly healing skin grafts should be performed under the supervision of the attending physician.

Do not apply to dying wounds.

Effect on the ability to drive transp. cf. and fur:

The drug does not affect the ability to drive vehicles and mechanisms.

Form release / dosage:

Ointment for external use, 5%.

Packaging:

By 25, 30, 35 or 50 grams into aluminum tubes with screw-on caps.

By 5, 10, 15, 20, 25, 30, 35 or 50 g in cans of dark glass such as BTS made of glass fiber with pull-on lids. The label is self-adhesive on the can.

Each tube or jar, together with the instruction for use, is placed in a cardboard package (pack) of cardboard for consumer containers.

Storage conditions:

In the dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-002626

Date of registration:22.09.2014

Date of cancellation:2019-09-22

The owner of the registration certificate:ATOLL, LLC ATOLL, LLC Russia

Manufacturer: & nbsp

OZONE, LLC Russia

Representation: & nbspOZONE LLC OZONE LLC Russia

Information update date: & nbsp08.01.2016

Illustrated instructions

Instructions

D-Panthenol (D-Panthenol)