Active substanceDexpanthenolDexpanthenol
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  • Dosage form: & nbspcream for external use
    Composition:

    1 g of cream contains

    active substance: dexpanthenol 50 mg;

    Excipients: 100 mg of propylene glycol, methyl parahydroxybenzoate 0.8 mg propyl parahydroxybenzoate 0.2 mg, 16 mg tsetostearat macrogol cetostearyl alcohol [cetyl alcohol not more than 60%, stearyl alcohol of not less than 40%] 40 mg liquid paraffin 80 mg petrolatum 100 mg sodium hydrogen phosphate dodecahydrate 0.2 mg, 7.8 mg potassium dihydrogen phosphate, purified water to 1 g

    Description:

    The cream is white or almost white.

    Pharmacotherapeutic group:Regeneration of tissue stimulant
    ATX: & nbsp

    D.03.A.X.03   Dexpanthenol

    S.01.X.A.12   Dexpanthenol

    D.03.A.X   Other drugs that promote normal scarring

    S.01.X.A   Other drugs for the treatment of eye diseases

    Pharmacodynamics:Dexpanthenol is a derivative of pantothenic acid. Dexpanthenol passes into the body in pantothenic acid, which is an integral part of coenzyme A and is involved in the processes of acetylation, in the synthesis of acetylcholine, corticosteroids, porphyrins. Furthermore, participates in almost all metabolic processes (tricarboxylic acid cycle, metabolism of carbohydrates, fats and fatty acids, phospholipids, proteins and others.), Stimulates the regeneration of the skin, mucous membranes, normalizes cell metabolism, accelerates mitosis and increases the strength of collagen fibers.It has a regenerating, metabolic and weak anti-inflammatory effect.
    Pharmacokinetics:

    When applied externally, it is quickly absorbed by the skin and converted to pantothenic acid, binds to plasma proteins (mainly with beta-globulin and albumin). Its concentration in the blood is 0.5-1 mg / l, in the blood serum - 100 μg / l. Pantothenic acid is not metabolized in the body (except for inclusion in To-A), is displayed unchanged.

    Indications:

    When the integrity of the skin is broken: healing of burns (including sunburn), minor skin lesions (abrasions, cuts, cracks, etc.).

    Prevention and treatment of skin dryness, including as a consequence of dermatitis of various genesis (manifested by peeling, redness, irritation, feeling of tightness), as well as daily care for skin areas exposed to the greatest impact of external factors (face, hands), including due to weathering.

    For the care of the mammary gland during lactation (cracks and reddening of the nipples of the breast), to care for infants and infants (diaper rash, "diaper" dermatitis).

    Contraindications:

    Hypersensitivity to the components of the drug.

    Pregnancy and lactation:

    The drug can be used during pregnancy and during breastfeeding. If the drug is used to treat nipple cracks during lactation, it should be washed off before breast-feeding.

    Dosing and Administration:

    Outwardly. The cream is applied a thin layer 1-2 times a day on the previously cleaned, dry skin and lightly rubbed.

    When caring for the mammary gland, the cream is applied to the nipple surface after each feeding.

    When caring for infants, the cream is applied at every change of diapers (diapers, diapers).

    Side effects:

    Allergic reactions. Allergic skin reactions (eg, contact dermatitis, allergic dermatitis, itching, redness, eczema, rash, hives, skin irritation). If any of the side effects indicated in the manual are aggravated, or any other side effects not indicated in the instructions are noted, you should inform the doctor immediately.

    Overdose:

    Cases of overdose are unknown.

    Interaction:Cases of interaction with other drugs are unknown.
    Special instructions:

    For external use only. Do not apply to dying wounds.

    Effect on the ability to drive transp. cf. and fur:

    The drug does not affect the ability to drive vehicles or engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

    Form release / dosage:

    Cream for external use 5%.

    Packaging:

    25 g or 50 g in aluminum tubes.

    Each tube together with instructions for the use of the drug is placed in a pack of cardboard.

    Storage conditions:

    At a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years. Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:LP-004618
    Date of registration:26.12.2017
    Expiration Date:26.12.2022
    The owner of the registration certificate:NIZHFARM, JSC NIZHFARM, JSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp24.01.2018
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