Erythromycin (Erythromycin)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceErythromycinErythromycin
Dosage form: & nbspointment for external use
Composition:

Active substance:


Erythromycin

1.11 g

Excipients:


sodium disulfite (sodium metabisulphite)

0.01g

propyl parahydroxybenzoate (nipazole)

0.02 g

methylparahydroxybenzoate (nipagine)

0.12 g

anhydrous lanolin

40.0 grams

petrolatum

up to 100 g

Note. The amount of erythromycin is indicated for a drug with an activity of 900 U / mg. In the case of a higher activity of erythromycin, accordingly, its amount is reduced.

Description:Ointment is yellowish or brownish-yellow in color.
Pharmacotherapeutic group:antibiotic-macrolide
ATX: & nbsp

S.01.A.A.17   Erythromycin

J.01.F.A.01   Erythromycin

Pharmacodynamics:Bacteriostatic antibiotic from the group of macrolides. With external application has antibacterial and anti-acne action. Reversibly binds to 50S subunit of ribosomes, which disrupts the formation of peptide bonds between amino acid molecules and blocks the synthesis of proteins of microorganisms (does not affect the synthesis of nucleic acids). When used in high doses depending on the type of pathogen can exhibit bactericidal action.
Indications:

Infections of the skin and soft tissues (pustular skin diseases, including acne vulgaris, infected wounds, bedsores, burns of II-III degree, trophic ulcers).

Contraindications:

Hypersensitivity.

Pregnancy and lactation:

Sufficient experience in the use of the drug during pregnancy and during lactation there. It is possible to apply the drug to the prescribing doctor if the expected therapeutic effect exceeds the risk of possible side effects.

Dosing and Administration:

Outer: applied to affected skin 2-3 times a day, with burns - 2-3 times a week, the duration of treatment - 1,5-2 months.

Side effects:

Local reactions: hyperemia, burning, itching, irritation and peeling of the skin.

Interaction:

Incompatible with lincomycin, clindamycin and chloramphenicol (antagonism).

Reduces the bactericidal action of beta-lactam antibiotics (penicillins, cephalosporins, carbopenems).

With the simultaneous use of medicinal forms of erythromycin for external use with abrasive substances, leading to excessive skin irritation, as well as with drugs that cause skin peeling, a cumulative irritating or drying effect is possible.

Special instructions:

Before using any other anti-acne medication for external use, it should take at least 1 hour.

If within 3-4 weeks the condition of acne does not improve, you should consult a doctor (for a full therapeutic effect, it may take 2-3 months).

With prolonged use, it is possible to develop superinfection.

Effect on the ability to drive transp. cf. and fur:

During the period of treatment, it is possible to manage motor vehicles and engage in other potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.

Form release / dosage:

Ointment for external use, 10 000 units / g.

Packaging:

For 15 g in tubes of aluminum.

One tube together with the instruction for use is placed in a pack of cardboard.

Storage conditions:

In a dry place at a temperature not exceeding 20 ° ะก.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:On prescription
Registration number:LS-002688
Date of registration:12.07.2011
The owner of the registration certificate:BIOSINTEZ, PAO BIOSINTEZ, PAO Russia
Manufacturer: & nbsp
Representation: & nbspBIOSINTEZ JSC BIOSINTEZ JSC Russia
Information update date: & nbsp29.09.2015
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