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Single dose for adults and adolescents, over 14 years, is 250-500 mg, daily -1.2 g. The interval between prescription is 6 hours.In severe infections, the daily dose can be increased to 4 g.
Children from 3 to 18 years, depending on the age, body weight and severity of infection - 30-50 mg / kg / day in 3-4 hours. In case of more severe infections, the dose can be doubled.
For the treatment of diphtheria carriage - 250 mg twice a day.
With amoebic dysentery adults - 250 mg 4 times a day, children - 30-50 mg / kg / day; the duration of the course is 10-14 days.
When legionellosis - 500-1000 mg 4 times a day for 14 days.
With gonorrhea - 500 mg every 6 hours for 3 days, then 250 mg every 6 hours for 7 days.
In tonsillitis, adults with pharyngitis - 20-50 mg / kg / day, children - 20-30 mg / kg / day, the course duration - at least 10 days.
For prevention of septic endocarditis in patients with heart defects, 1 g for adults and 20 mg / kg for children, 1 hour before the therapeutic or diagnostic procedure, then 0.5 g for adults and 10 mg / kg for children, again in 6 hours.
In whooping cough - 40-50 mg / kg / day for 5-14 days.
When pneumonia in children - 50 mg / kg / day in 4 divided doses, for at least 3 weeks.
When urogenital infections during pregnancy - 500 mg 4 times a day for 7 days or (with tolerability) - 250 mg 4 times a day for 14 days.
In adults, with uncomplicated chlamydia and intolerance to tetracyclines - 500 mg 4 times a day for at least 7 days.