Nicotinic acid - instructions for use, dose, side effects, contraindications

Nicotinic acid is a specific antipellar agent (vitamin PP). It improves carbohydrate metabolism, has a vasodilating effect, including on the vessels of the brain, has lipid-lowering activity. In large doses of 3-4 grams per day a nicotinic acid reduces the content of triglycerides and lipoproteins of low blood density, reduces the choleste ratioRhin / phospholipids at low density lipoproteins. It has detoxification properties.

Pharmacokinetics:

Indications:

Prophylaxis and treatment of pellagra (PP vitamin deficiency); complex therapy ischemic disorders of cerebral circulation, obliterating diseases of the vessels of the extremities (obliterating endarteritis, Raynaud's disease) and kidneys, complications of diabetes mellitus (diabetic polyneuropathy, microangiopathy); liver diseases (acute and chronic hepatitis), gastritis with low acidity, neuritis of the facial nerve, various intoxications (professional, medicamentous,alcoholic), long-term non-healing wounds and ulcers.

Contraindications:

Hypersensitivity to the drug. Peptic ulcer of stomach and 12-colon (in the stage of exacerbation); severe arterial hypertension; podagra; hyperuricemia, nephrolithiasis, liver disease, hereditary diabetes mellitus. Pregnancy and the period of breastfeeding.

Pregnancy and lactation:contraindicated

Dosing and Administration:

It is used according to the doctor's prescription.

Nicotinic acid tablets are taken orally after a meal. As antipellargicheskoe means nikotnkazyu acid prescribed adult 0.1 g 2-4 times a day (the highest daily dose of 0.5 g). Children are prescribed from 0.0125 to 0.05 g 2-3 times a day, depending on the age. The course of treatment is 15-20 days.

Adults with ischemic disorders of cerebral circulation, spasms of the vessels of the extremities, gastritis with low acidity, neuritis of the facial nerve, wounds and ulcers nicotinic acid is recommended to be administered in a single dose of 0.05-0.1 g, in a daily dose - up to 0.5 g. The course of treatment - 1 month

Side effects:

There may be allergic reactions, dizziness, redness of the face, a sense of tidal flow to the head, paresthesia.In this case, you should reduce the dose or cancel the drug. With prolonged use of large doses of nicotinic acid, it is possible to develop fatty liver dystrophy, hyperuricemia, increased hepatic activity traasaminases and alkaline phosphatase, a decrease in glucose tolerance.

Overdose:

Interaction:It is necessary to consult a doctor if a nicotinic acid will be applied simultaneously with other medicinal products.

Special instructions:

To prevent complications from the liver (with prolonged use in large doses) it is recommended to include in the diet products rich in methionine (cottage cheese) or use methionine, lipoic acid, essential oil and other lipotropic agents. With caution should be used for gastritis with high acidity, peptic ulcer disease and duodenal ulcer (in the anamnesis).

During the treatment with nicotinic acid (especially in large doses), liver function should be closely monitored.

Effect on the ability to drive transp. cf. and fur:

Form release / dosage:

50 tablets in cans of polymer with screw cap. Every The bank together with the instruction on

medical application is placed in a pack or 60 cans with an equal number of instructions for use are placed in a group package.

Packaging:(50) - polymer cans (1) / with instruction for use / - packs cardboard
(50) - polymer cans (60) / group packaging: with an equal number of instructions for use / - cardboard boxes

Storage conditions:

At a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

4 years. Do not use the drug after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LS-000981

Date of registration:26.03.2010

The owner of the registration certificate:PHARMSTANDART-UFIM VITAMIN FACTORY, OJSC PHARMSTANDART-UFIM VITAMIN FACTORY, OJSC Russia

Manufacturer: & nbsp

PHARMSTANDART-UFIM VITAMIN FACTORY, OJSC Russia

Information update date: & nbsp11.08.2015

Illustrated instructions

Instructions

A nicotinic acid (Nicotinic acid)