Nicotinic acid - instructions for use, dose, side effects, contraindications

Nicotinic acid is a specific antipellagic agent (vitamin PP). It improves carbohydrate metabolism, has a vasodilating effect, including on the vessels of the brain, has lipid-lowering activity. In large doses a nicotinic acid reduces the content of triglycerides and p-lipoproteins in the blood, reduces the ratio of cholesterol / phospholipids in low-density lipoproteins. It has detoxification properties.

Indications:

The nicotinic acid is prescribed for the prevention and treatment of pellagra (RV avitaminosis), in the complex therapy of ischemic disorders of cerebral circulation, vascular disease of the extremities (obliterating endarteritis, Raynaud's disease), spasm of the vessels of the extremities, biliary and urinary tracts, complications of diabetes mellitus (diabetic polyneuropathy, microangiopathy ), liver disease (acute and chronic hepatitis),with gastritis with low acidity, as well as with neuritis of the facial nerve, with long-term non-healing wounds and trophic ulcers.

Contraindications:

Increased individual sensitivity to the drug.

Pregnancy and the period of feeding.

Peptic ulcer of stomach and duodenum (at the stage of exacerbation), expressed violations of liver function, gout and hyperuricemia, severe forms of hypertension and atherosclerosis, children's age (up to 3 years).

Carefully:Hemorrhagia, glaucoma, hepatic insufficiency, arterial hypotension, hyperacid gastritis, peptic ulcer and 12 duodenal ulcer (outside exacerbation).

Dosing and Administration:

Nicotinic acid tablets are taken orally after a meal.

As an antipellagic drug, nicotinic acid is prescribed for adults to 0.1 g (2 tablets) 2-4 times a day (the highest daily dose is 0.5 g).

Children are prescribed, starting from 3 years, to 0.05 g 2-3 times a day, depending on the age. The course of treatment is 15-20 days.

Adults with ischemic disorders of cerebral circulation, spasms of the vessels of the extremities, gastritis with low acidity, neuritis of the facial nerve, wounds and ulcers nicotinic acid is recommended in a single dose of 0.05-0.1 g, in a daily dose - up to 0.5 g. - 1 month. Repeated courses - on the advice of a doctor.

Side effects:

Allergic reactions are possible. When taking high doses orally: hyperemia of the face and upper body, paresthesia, dizziness, blood flushes to the skin of the face, arrhythmia, orthostatic hypotension, diarrhea, dry skin and eye mucosa, hyperglycemia, hyperuricemia, myalgia, nausea, vomiting, peptic ulcer, debilitating itching. With prolonged use - fatty liver disease, hyperuricemia, decreased glucose tolerance, increased concentrations in the blood of aspartate aminotransferase, lactate dehydrogenase, alkaline phosphatase, a feeling of heat, hyperemia of the skin (especially face and neck), headache, dizziness, asthenia.

Overdose:

Interaction:

It is necessary to consult a doctor if a nicotinic acid will be applied simultaneously with other drugs.

Care should be taken when combining with hypotensive drugs, anticoagulants and acetylsalicylic acid.

Special instructions:

To prevent complications from the liver (with prolonged use in large doses) it is recommended to include in the diet products rich in methionine (cottage cheese) or take methionine, lipoic acid, and other lipotropic agents.

During the treatment with nicotinic acid (especially large doses), liver function should be carefully monitored.

Form release / dosage:

Tablets 50 mg.

10 tablets per contour packing.

5 contour packs together with instructions on medical application is placed in a pack of cardboard.

Packaging:(10) - packings, cellular planimetric (5) - packs cardboard

Storage conditions:

In a dry, sheltered from the world place, with temperature from 15 ° С to 25 ° С. Keep out of the reach of children.

Shelf life:

4 years.

After expiration date the drug should not be used.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-006554/09

Date of registration:17.08.2009

The owner of the registration certificate:AVEKSIMA, JSC AVEKSIMA, JSC Russia

Manufacturer: & nbsp

IRBITSK HFZ, OJSC Russia

Information update date: & nbsp11.08.2015

Illustrated instructions

Instructions

A nicotinic acid (Nicotinic acid)