Active substanceTroxerutinTroxerutin
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  • Dosage form: & nbspgel for external use
    Composition:

    Active substance: troxerutin - 2.0 g.

    Excipients: carbomer (arepol, polyacrylate, rare) - 0.60 g, sodium hydroxide - 0.132 g, disodium edetate - 0.05 g, benzalkonium chloride - 0.575 g, purified water - up to 100.0 g.

    Description:Transparent gel from yellow to light brown or yellow-green color.
    Pharmacotherapeutic group:Venotonizing and venoprotective agent
    ATX: & nbsp

    C.05.C.A   Bioflavonoids

    C.05.C.A.04   Troxerutin

    Pharmacodynamics:

    Troxerutin is a flavonoid (derivative routine), has P-vitamin activity, venotonic, venoprotective, anti-edematous, antioxidant, anti-inflammatory action. Troxerutin participates in oxidation-reduction processes, blocks hyaluranidase, stabilizes hyaluronic acid of cell membranes and reduces permeability and fragility of capillaries, increases their tone. Increases the density of the vascular wall, reduces exudation of the liquid part and diapedesis of blood cells. Reduces inflammation in the vascular wall, limiting the adhesion of platelets to its surface.

    Pharmacokinetics:When applying the gel to the affected area, the active substance quickly penetrates the epidermis, after 30 minutes it is found in the dermis, and after 2-5 hours in the subcutaneous adipose tissue.
    Indications:

    - Phlebeurysm;

    - chronic venous insufficiency with such manifestations as edema, pain, heaviness in the lower limbs;

    - superficial thrombophlebitis, periphlebitis, phlebothrombosis;

    - postthrombotic syndrome;

    - post-traumatic edema, hematomas;

    - prevention of complications after vein operations;

    - hemorrhoids.

    Contraindications:

    Violation of the integrity of the skin and hypersensitivity to the drug.

    Children up to 15 years.

    Carefully:

    Renal failure (prolonged use).

    Pregnancy and lactation:

    Data on the undesirable effects on the fetus and the newborn when using the drug there.

    Reception of the drug Troxerutin contraindicated in the first trimester of pregnancy. In the II and III trimester of pregnancy, as well as during breastfeeding, the medication can be used only as directed by the doctor.

    Dosing and Administration:

    Outwardly. The gel is applied to the affected area 2 times a day, morning and evening, gently massage massaging until completely absorbed. If for any reason the use of the drug is missed, the patient can apply it at any time, observing the interval between treatment sessions of at least 10-12 hours.

    The dose of the drug depends on the area of ​​the damaged surface, but should not exceed 3-4 cm of gel (1.5-2 g). If necessary, the gel can be applied under bandages or elastic stockings.

    The success of the drug treatment depends to a large extent on its regular application for a long time. If the symptoms of the disease worsen or do not go away after 6-7 days of daily use, the patient should consult a doctor who will prescribe further treatment and determine the duration of the course.

    Side effects:

    In rare cases, there are allergic skin reactions - urticaria, eczema, dermatitis, rash, redness of the skin and itching.

    If side effects occur that are not described in this manual, stop taking the medication and tell your doctor.

    Overdose:

    Cases of overdose with topical application are not described.

    Interaction:

    Currently, data on the drug drug interaction Troxerutin are absent.

    Special instructions:

    The gel is applied only to the undamaged surface.

    Avoid contact with open wounds, eyes and mucous membranes.

    After applying the product, you should wash your hands.

    In conditions characterized by increased vascular permeability (including scarlet fever, influenza, measles, allergic reactions), the gel is used in combination with ascorbic acid to enhance its effect.

    Effect on the ability to drive transp. cf. and fur:

    The use of the drug does not affect the ability to perform potentially dangerous activities requiring increased concentration and speed of psychomotor reactions (vehicle management, work with moving mechanisms, dispatcher and operator work).

    Form release / dosage:Gel for external use, 2%.
    Packaging:

    By 30.0 or 40.0 grams in tubes of aluminum with bushons with an internal lacquer coating.

    Each tube, together with the instruction for medical use, is placed in a pack of cardboard.

    Storage conditions:

    In a dry, the dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    5 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-004124
    Date of registration:08.02.2017
    Expiration Date:08.02.2022
    The owner of the registration certificate:GREEN DUBRAVA, CJSC GREEN DUBRAVA, CJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp05.03.2017
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