Troxerutin - instructions for use, doses, side effects, contraindications

Excipients: trolamine (triethanolamine) - 7.0 mg: carbomer - 6.0 mg; benzalkonium chloride solution 50% - 1.0 mg (in terms of 100% substance); Dinagria edetat - 0.5 mg; purified water - up to 1.0 g.

Description:

Homogeneous transparent gel from yellow or greenish-yellow to light brown in color.

Pharmacotherapeutic group:Venotonizing and venoprotective agent

ATX: & nbsp

C.05.C.A Bioflavonoids

C.05.C.A.04 Troxerutin

Pharmacodynamics:Troxerutin is a derivative of rutin (flavonoid), it has P-vitamin activity; has venotonic, angioprotective, anti-edematous, antioxidant and anti-inflammatory effects. Troxerutin participates in oxidation-reduction processes, blocks hyaluronidase, stabilizes hyaluronic acid of cell membranes and reduces permeability and fragility of capillaries, increases their tone. Increases the density of the vascular wall, reduces exudation of the liquid part of the plasma and diapedesis of blood cells. Reduces inflammation in the vascular wall, limiting the adhesion of platelets to its surface.

Pharmacokinetics:

Suction, distribution, metabolism, excretion

When applying the gel to the skin troxerutin quickly penetrates the epidermis, after 30 minutes it is found in the dermis, and after 2-5 hours - in the subcutaneous adipose tissue.

Indications:

- Phlebeurysm;

- chronic venous insufficiency with such manifestations as edema, pain, sensation of heaviness in the legs;

- superficial thrombophlebitis, periphlebitis, phlebothrombosis;

- postthrombotic syndrome;

- post-traumatic edema, hematomas;

- prevention of complications after operations on veins;

- Hemorrhoids.

Contraindications:

- Pincreased sensitivity to troxerutin or to any other component of the drug;

- violation of the integrity of the skin;

- age up to 15 years.

Carefully:

- Pregnancy (1st trimester);

- Renal failure (prolonged use).

Pregnancy and lactation:

In the first trimester of pregnancy, the use of a medicinal product Troxerutin contraindicated due to lack of clinical experience. In the II and III trimesters of pregnancy, the drug Troxerutin is possible only if the expected benefit to the mother exceeds the potential risk to the fetus. Data on the penetration of the drug into breast milk are not available. A drug Troxerutin should not be used during breastfeeding.

Dosing and Administration:

Outwardly.

Gel Troxerutin Apply morning and evening to the skin above the painful area with the help of light massaging movements until it is completely absorbed into the skin. The dose of the drug depends on the area of the damaged surface, but should not exceed 3-4 cm of gel (1.5-2 g). If for any reason the use of the drug is missed, the patient can apply it at any time, observing the interval between treatment sessions of at least 10-12 hours.

If necessary, the gel can be applied under the occlusive dressing.

It is recommended to combine with the reception of capsules containing troxerutin, to enhance the impact.

If the symptoms of the disease worsen or do not go away after 6-7 days of daily use of the drug, you should see a doctor who will prescribe further treatment and determine the duration of the course of therapy.

Side effects:

In rare cases, there are allergic reactions (redness of the skin, itching, rash). These symptoms quickly disappear after discontinuation of treatment.

If side effects occur that are not described in this manual, stop taking the medication and tell your doctor.

Overdose:

Cases of overdose with topical application are not described.If you accidentally swallow the drug, there may be burning sensation in the oral cavity, salivation, nausea, vomiting. In this case, washing of the oral cavity of the stomach is shown, if necessary, symptomatic treatment.

Interaction:

There is no data on the interaction of troxerutin in this dosage form and other drugs.

Special instructions:

The gel is applied only to the undamaged surface. Avoid contact with open wounds, eyes and mucous membranes! After applying the product, you should wash your hands. In conditions characterized by increased vascular permeability (including scarlet fever, influenza, measles, allergic reactions), the gel is used in combination with ascorbic acid to enhance the effect.

Effect on the ability to drive transp. cf. and fur:

The use of the drug does not affect the ability to perform potentially dangerous activities requiring increased concentration and speed of psychomotor reactions (vehicle management, work with moving mechanisms, dispatcher and operator work).

Form release / dosage:

Gel for external use 2%.

Packaging:

For 50 g or 100 g in tubes of aluminum.Each tube together with the instruction for use is placed in a pack of cardboard.

It is allowed to bundle 2 packs of cardboard in a group box of cardboard.

Storage conditions:

At a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-004467

Date of registration:19.09.2017

Expiration Date:19.09.2022

The owner of the registration certificate:VERTEKS, AO VERTEKS, AO Russia

Manufacturer: & nbsp

VERTEKS, AO Russia

Information update date: & nbsp05.10.2017

Illustrated instructions

Instructions

Troxerutin (Troxerutin)