Troxerutin-MIC - instructions for use, doses, side effects, contraindications

Composition of gelatin capsule shell: gelatin - 61.624 mg, glycerol - 0,193 mg, water purified - 10,585 mg, sodium lauryl sulfate - 0.049 mg, titanium dioxide - 0.497 mg, dyes: quinoline yellow E-104-0.042 mg, solar sunset yellow E-110-0.01 mg.

Description:

Capsules hard gelatine № 1 cylindrical shape with hemispherical ends of yellow color. The contents of the capsules are an amorphous powder or a pre-pressed column of powder that is easily broken by a glass rod, yellow and odorless.

Pharmacotherapeutic group:venotonic and venoprotective agent

ATX: & nbsp

C.05.C.A Bioflavonoids

C.05.C.A.04 Troxerutin

Pharmacodynamics:

Angioprotective agent acts mainly on capillaries and veins.

Reduces the pores between endothelial cells by modifying a fibrous matrix located between endothelial cells. Inhibits aggregation and increases the degree of erythrocyte deformability; has anti-inflammatory effect.

With chronic venous insufficiency reduces the severity of edema, pain, seizures, trophic disorders, varicose ulcers, alleviates the symptoms associated with hemorrhoids - pain, itching and bleeding.

Due to the favorable effect on the permeability and resistance of the capillary walls, it helps to slow the development of diabetic retinopathy.In addition, its effect on the rheological properties of blood contributes to the prevention of microthrombosis of the retinal vessels.

Pharmacokinetics:

After intake, the absorption is about 10-15%. Maximum plasma concentrations are achieved on average 2 hours after admission, the therapeutic level in the plasma persists for 8 hours. Metabolized in the liver with the formation of 2 metabolites. It is excreted by the kidneys and with bile (11% unchanged) during the day.

Indications:Varicose veins, chronic venous insufficiency with such manifestations as static heaviness in the legs, ulcers of the lower leg, trophicskin rash, superficial thrombophlebitis, periphlebitis, phlebothrombosis, shin ulcers, dermatitis, hemorrhoidsth, postthrombotic syndrome, diabetic mikroangiopathyI, retinopathy, hemorrhagic diathesis(increased permeabilitycapillary tubes), incl. measles, scarlet fever, influenza, side effects of radiotherapy, post-traumatic edema, hematoma, prevention of complications after vein operations.

Contraindications:

Hypersensitivity, peptic ulcer of the stomach and duodenum, chronic gastritis (in the phase of exacerbation), pregnancy (I trimester), the period of breastfeeding.

Carefully:

Renal failure (prolonged use).

Pregnancy and lactation:

It is not recommended to appoint during pregnancy (I trimester) and during breastfeeding. Use the drug in the II and III trimesters of pregnancy should be only if the expected benefit for the mother prevails over the possible risk to the fetus.

Dosing and Administration:

The drug is taken orally during meals, with plenty of water.

Initial dose - 1 capsule 3 times in day; maintenance therapy - 1 -2 capsules per day. The course of treatment is 2-4 weeks.

To mitigate the adverse side effects of radiation therapy, the drug is prescribed in higher doses. Duration of treatment - up to 2 months.

Side effects:In some cases, erosive-ulcerative lesions of the gastro-gastrointestinal tract, allergic reactions (skin rash), headache.

Overdose:

Possible appearance of the following symptoms: agitation, nausea, headache, flushes of blood to the face.

Treatment: it is necessary to rinse the stomach, take Activated carbon. If necessary, start symptomatic treatment.

Interaction:Strengthens the action of ascorbic acid on the structure and permeability of the vascular wall.

Special instructions:

In order for the expected therapeutic result to appear, you must strictly follow the doctor's instructions for dosage and duration of treatment.

You can use the drug as one of the components of complex treatment. In particular, in conditions characterized by increased vascular permeability and a violation of their structure (in scarlet fever, influenza, measles, allergic reactions), they are used in combination with ascorbic acid to enhance its effects.

It is not recommended to prolong use for patients with severe renal dysfunction.

Effect on the ability to drive transp. cf. and fur:Does not affect.

Form release / dosage:Capsules 200 mg.

Packaging:

For 10 capsules in a planar cell package, 5 contour squares (blisters) together with instructions for use in a pack of cardboard.

Storage conditions:

Store in a dry, protected from light place at a temperature of 15 to 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years. Do not use after the expiration date.

Terms of leave from pharmacies:On prescription

Registration number:П N014572 / 01

Date of registration:25.02.2010

The owner of the registration certificate:MINSKINTERKAPS, UP MINSKINTERKAPS, UP Republic of Belarus

Manufacturer: & nbsp

MINSKINTERKAPS, UP Republic of Belarus

Representation: & nbspMINSKINTERKAPS MINSKINTERKAPS Republic of Belarus

Information update date: & nbsp24.10.2015

Illustrated instructions

Instructions

Troxerutin-MIC (Troxerutin-MIK)