Flavonoid (derivative of routine), has P-vitamin activity; has venotonic, angioprotective, anti-inflammatory and anti-edematous action; reduces permeability and fragility of capillaries.
Its pharmacodynamic properties are associated with the participation of trouxerutin bioflavonoids in oxidation-reduction processes and inhibition of hyaluronidase. By suppressing hyaluronidase, troxerutin stabilizes the hyaluronic acid of cell membranes and reduces their permeability. It has antioxidant activity, which prevents oxidation of ascorbic acid, adrenaline and lipids. In addition, it reduces permeability and fragility of capillaries, prevents damage to the basement membrane of endothelial cells when various factors influence it. Troxerutin reduces exudative inflammation in the vascular wall, limiting the adhesion of platelets to its surface. As a result of treatment with troxerutin, the sense of heaviness in the legs disappears, the swelling of tissues decreases, and trophicity improves.