Iodine - instructions for use, dose, side effects, contraindications

Antiseptic. The main active substance is molecular iodine, which has an antiseptic property. When applied to large areas of the skin iodine has a resorptive effect: participates in the synthesis of T3 and T4, actively affects the metabolism, enhances the processes of dissimilation, participates in the synthesis of thyroxine and triiodothyronine, has a proteolytic effect, in large quantities - inhibits the function of the thyroid gland. Has a local irritating and distracting effect. Alcohol slows the excretion of iodine and reduces its irritating effect on tissues. It has a bactericidal effect on both gram-positive and gram-negative flora (most active on streptococcal flora and Escherichia coli), as well as pathogenic fungi and yeast.A more stable flora is staphylococcus, but with prolonged use of the drug in 80% of cases, staphylococcal flora is suppressed. Pseudomonas aeruginosa is stable, the drug is low-toxic.

Pharmacokinetics:

Upon contact with the skin, 30% turns into iodide, the rest - into the active iodine. Partially absorbed. The absorbed part penetrates into tissues and organs, is selectively absorbed by the thyroid gland. It is allocated by kidneys (mainly), intestines, sweat glands, with milk during lactation.

Indications:

Inflammatory and infectious skin diseases, abrasions, cuts, microtrauma, wounds, myositis, neuralgia, inflammatory infiltrates; treatment of the edges of wounds, skin before injections, punctures, catheterization.

Contraindications:

Hypersensitivity, thyrotoxicosis, herpetiform dermatitis.

Carefully:

Pregnancy, lactation, children's age.

Dosing and Administration:

External, lubricate the affected or subject to treatment areas of the skin.

Side effects:

Skin irritation, allergic reactions (skin itching), with prolonged use on extensive wound surfaces - iodism (rhinitis, urticaria, Quincke's edema, salivation, lacrimation, acne).

Interaction:

Pharmaceutically incompatible with essential oils, solutions of ammonia, white sedimentary mercury (an explosive mixture is formed); disinfecting drugs containing Hg, enzymes, reducing agents, alkalis.

Special instructions:

Light and temperature above 40 ° C accelerates the decomposition of active iodine.

The drug should have a dark brown color. Discoloration of the solution indicates the destruction of the complex with the transition of active iodine to iodide ion and a decrease in the effectiveness of the preparation.

Avoid contact with eyes. Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity.

Effect on the ability to drive transp. cf. and fur:No data available.

Form release / dosage:

Solution for external use alcohol, 5%.

Packaging:

1, 5, 10, 25, 100 ml into the glass bottles; or in polymeric bottles, corked with polymer caps, polymer screw caps or aluminum screw caps; or in polymeric vials, disposable hermetic, which can be combined with a basis of 4, 5, 6 pieces.

On bottles and bottles stick a label of paper label or writing, or self-adhesive.

On the vials, polymer disposable hermetic labeling can be applied by thermal printing.

4, 5, 6, 8, 10, 12 vials of polymer disposable sealed are mixed together with instructions for use in a pack of cardboard for consumer packaging.

Bottles or bottles, together with an equal number of instructions for use, or packs of vials with disposable, non-reusable plastic bottles with instructions for use, are placed in boxes of corrugated cardboard.

Storage conditions:

In the dark place at a temperature of 2 to 15 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-000765

Date of registration:29.09.2011

Expiration Date:29.09.2016

The owner of the registration certificate:LYUMI, LLC LYUMI, LLC Russia

Manufacturer: & nbsp

LYUMI, LLC Russia

Representation: & nbspLYUMI, LLCLYUMI, LLC

Information update date: & nbsp16.11.2017

Illustrated instructions

Instructions

Iodine (Iodum)