Active substanceIodine + [Potassium iodide + Ethanol]Iodine + [Potassium iodide + Ethanol]
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  • Dosage form: & nbspsolution for external use [alcohol]
    Composition:

    Active substance: iodine 50 g;

    Excipients: potassium iodide 20 g, ethanol (ethyl alcohol) 95%, purified water evenly to 1000 ml.

    Description:

    Transparent liquid of red-brown color with a characteristic smell.

    Pharmacotherapeutic group:Antiseptic
    ATX: & nbsp

    D.08.A.G.03   Iodine

    Pharmacodynamics:

    Antiseptic. The main active substance is molecular iodine, which has an antiseptic property. When applied to large areas of the skin iodine has a resorptive effect; participates in the synthesis of thyroxine and triiodothyronine.

    Has a bactericidal effect on both gram-positive and gram-negative flora (most active - on Streptococcus spp. and Escherichia coli), as well as pathogenic fungi and yeast. Most strains Staphylococcus spp. are stable, however, with prolonged use of the drug in 80% of cases, staphylococcal flora is suppressed. Pseudomonas aeruginosa is stable.

    Pharmacokinetics:

    Upon contact with the skin, it is converted into iodides by 30%, and the rest into active iodine. Partially absorbed.The absorbed part penetrates into tissues and organs, is selectively absorbed by the thyroid gland. It is excreted by the kidneys (mainly), intestines, sweat glands, with breast milk during lactation.

    Indications:

    Inflammatory and infectious diseases of the skin, abrasions, cuts, microtrauma, wounds, inflammatory infiltrates; treatment of the edges of wounds, skin before injections, punctures, catheterization.

    Contraindications:

    Hypersensitivity, thyrotoxicosis, herpetiform dermatitis.

    Carefully:

    Childhood.

    Pregnancy and lactation:

    It is not recommended to use the drug during pregnancy.

    Application in the period of breastfeeding is possible if the expected benefit for the mother exceeds the potential risk for the child. It is necessary to consult a doctor.

    Dosing and Administration:External, lubricate the affected or subject to treatment areas of the skin.
    Side effects:

    Skin irritation, allergic reactions (itchy skin); with prolonged use on extensive wound surfaces - iodism (rhinitis, urticaria, Quincke's edema, excessive salivation, lacrimation, acne).

    Overdose:

    In case of an overdose, iodism, irritation and skin burns are possible.

    Treatment: symptomatic; rinse excess product with clean running water.
    Interaction:

    Pharmaceutically incompatible with essential oils, ammonia solutions, enzymes, reducing agents and alkalis, with disinfecting drugs containing Hg; with white sedimentary mercury (mercury amidochloride) an explosive mixture is formed.

    Special instructions:

    Light and temperature above 40 ° C accelerate the decay of active iodine. The drug should have a dark brown color. Discoloration of the solution indicates the destruction of the complex with the transition of active iodine to iodide ion and a decrease in the effectiveness of the preparation.

    Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity.

    Avoid contact with eyes.

    Effect on the ability to drive transp. cf. and fur:The use of the drug according to the instructions for medical use does not adversely affect the performance of hazardous activities requiring special attention and quick reactions.
    Form release / dosage:

    Solution for external use (alcohol), 5%.

    Packaging:

    To 10 ml in bottles of orange glass for a solution of ammonia and alcohol solution of iodine, sealed with polyethylene threaded caps with a sealing element.

    To 10, 25, 50, 100 ml in bottles of orange glass, sealed with stoppers plastic and screwed on lids or caps, screwed-on or capped with a screw-on cap with pomazkom.

    To 15, 25, 50 ml in the bottles-droppers, sealed with stoppers, polyethylene and screwed caps or stopper-droppers with lids made of polyethylene or polymeric materials.

    For 10, 15, 25, 50 ml into polyethylene terephthalate bottles, capped with screw capable polyethylene caps.

    Each bottle of 10, 15, 25, 50, 100 ml, together with the instruction for use, is placed in a pack of cardboard box.

    Vials by 10, 15, 25, 50, 100 ml with an equal number of instructions for use are placed in a group package (carton box).

    For 1 liter in bottles of orange glass, sealed with stoppers, polyethylene and screwed caps with instructions for use (for hospitals).

    1, 2, 5 l in polyethylene terephthalate bottles, capped with screw capped polyethylene caps with instructions for use (for hospitals).

    Storage conditions:

    In the dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the time specified on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-008998/10
    Date of registration:31.08.2010
    Expiration Date:Unlimited
    The owner of the registration certificate:LEKAR, LLC LEKAR, LLC Russia
    Manufacturer: & nbsp
    Representation: & nbspLEKAR, LLCLEKAR, LLCRussia
    Information update date: & nbsp17.11.2017
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