Iodine + [Potassium iodide + Ethanol] - instructions for use, doses, side effects, contraindications

Yodaminy forms and destroys microorganisms soaked, actively influences on metabolism, enhancing the dissimilation process; helps to lower the level of cholesterol in the blood.

Elementary iodine has pronounced antimicrobial properties. For preparations of elemental iodine, a pronounced local irritant effect on tissues is characteristic, and cauterizing effect in high concentrations. Local action is due to the ability of elementary iodine to precipitate tissue proteins. Preparations, eliminating the elementary iodine, have a much less pronounced irritant effect, and iodides have locally irritating properties only at very high concentrations.

The nature of the resorptive action of preparations of elemental iodine and iodides is the same. The most pronounced effect with resorptive action iodine preparations have on the functions of the thyroid gland.With iodine deficiency, iodides contribute to the restoration of impaired thyroid hormone synthesis. With normal iodine content in the environment, iodides inhibit the synthesis of thyroid hormones, reduce the sensitivity of the thyroid gland to thyroid-stimulating hormone pituitary gland and its pituitary secretion is blocked. The effect of iodine preparations on metabolism is manifested by the intensification of dissimilation processes. With atherosclerosis, they cause a slight decrease in the concentration of cholesterol and beta-lipoproteins in the blood; in addition, increase the fibrinolytic and lipoproteinase activity of blood serum and slow the rate of blood clotting.

Accumulating in syphilitic scales, iodine promotes their softening and resorption. However, the accumulation of iodine in tuberculosis foci leads to an intensification of the inflammatory process in them. Isolation of iodine excretory glands is accompanied by irritation of glandular tissue and increased secretion. This is due to expectorant action and stimulation of lactation (in small doses). However, in large doses of iodine preparations can cause suppression of lactation.

Pharmacokinetics:When exposed to skin or mucous membranes, 30% turns into iodides, and the rest into active iodine. Partially absorbed. The absorbed part penetrates into tissues and organs, is selectively absorbed by the thyroid gland. It is allocated mainly by the kidneys, intestines, sweat and mammary glands.

Indications:

Inflammatory diseases of skin and mucous membranes, abrasions, cuts, microtrauma, wounds; myositis, neuralgia (as a distraction); treatment of the edges of wounds, skin before injections, punctures, catheterization.

For topical use: chronic tonsillitis, atrophic rhinitis, purulent otitis, trophic and varicose ulcers, wounds, infected burns, fresh thermal and chemical burns of I-II degree.

For oral administration: prevention and treatment of atherosclerosis, tertiary syphilis.

ICD-10

IX.I70-I79.I70 Atherosclerosis

IX.I80-I89.I83.2 Varicose veins of the lower extremities with ulcer and inflammation

X.J30-J39.J31 Chronic rhinitis, nasopharyngitis and pharyngitis

X.J30-J39.J35.0 Chronic tonsillitis

XIII.M70-M79.M79.1 Myalgia

XIX.T08-T14.T14.0 Superficial injury of unspecified area of the body

XIX.T08-T14.T14.1 Open wound of unspecified area of the body

XIX.T20-T32.T30 Thermal and chemical burns, unspecified

Contraindications:

Hypersensitivity, pulmonary tuberculosis, nephritis, nephrosis, furunculosis, acne, chronic pyoderma, hemorrhagic diathesis, herpetiform dermatitis, urticaria.

Contraindicated for oral administration to children under 5 years.

Carefully:Children under 12 years.

Pregnancy and lactation:Use during pregnancy and breastfeeding with caution in accordance with the instructions. Contraindicated for oral administration during pregnancy.

Dosing and Administration:

Outer, on the damaged parts of the field.

Inside, dissolved in milk, after meals (dose set individually), adults for the prevention of atherosclerosis 1-10 drops 1-2 times a day for 30 days 2-3 times a year; for the treatment of atherosclerosis - 10-12 drops 3 times a day; with tertiary syphilis - 5-50 drops 2-3 times a day. The highest single dose - 20 drops, daily - 60 drops. Children older than 5 years are prescribed 3-5 drops 2-3 times a day, children under 5 are not prescribed. Higher doses of 5% solution for adults: single dose - 20 drops, daily - 60 drops.

Side effects:With prolonged use - iodizm (runny nose, Quincke's edema, salivation, lacrimation, acne on the skin and others). Skin irritation, allergic reactions (itchy skin).

Overdose:In case of an overdose, there may be phenomena of iodism, irritation, burns. Treatment symptomatic, rinse excess of the preparation with clean running water.

Interaction:Pharmaceutically incompatible with essential oils, solutions of ammonia, white sedimentary mercury (an explosive mixture is formed). Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity. Weaken the hypothyroid and strugogenic effects of lithium preparations.

Special instructions:

Light and temperature above 40 ° C accelerate the decomposition of active iodine. The drug should have a dark brown color. Discoloration of the solution indicates the destruction of the complex with the transition of active iodine to iodide ion and a decrease in the effectiveness of the preparation.

Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity.

Impact on the ability to drive vehicles and manage mechanisms

The use of the drug according to the instructions for medical use does not adversely affect the performance of potentially hazardous activities that require increased concentration of attention.

Avoid contact with the eyes.

Instructions

Iodine + [Potassium iodide + Ethanol] (Iodum + [Kalii iodidum + Spiritus aethylicus])