Iodine (Iodum)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceIodine + [Potassium iodide + Ethanol]Iodine + [Potassium iodide + Ethanol]
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    • Dosage form: & nbspsolution for external use [alcohol]
    Composition:

    Active substance: iodine 50 g;

    Excipients: potassium iodide 20 g, ethanol 95%, water cleared evenly to 1 l.

    Description:Transparent liquid of red-brown color with a characteristic smell.
    Pharmacotherapeutic group:Antiseptic
    ATX: & nbsp

    D.08.A.G.03   Iodine

    Pharmacodynamics:

    Antiseptic. The main active substance is molecular iodine, which has antiseptic properties. When applied to large areas of the skin iodine has a resorptive effect: actively affects the metabolism, is involved in the synthesis of thyroxine, has a proteolytic effect.

    It has a bactericidal effect, both on gram-positive flora (most active - on streptococcus and Escherichia coli), and on pathogenic fungi and yeast. Staphylococcus is more resistant flora, however, with prolonged use of the drug in 80% of cases it disappears. Pseudomonas aeruginosa is stable. The drug is low toxicity.

    Pharmacokinetics:

    When exposed to skin or mucous membranes, 30% turns into iodides, and the rest into active iodine. Partially absorbed.The absorbed part penetrates into tissues and organs, is selectively absorbed by the thyroid gland. It is allocated mainly by the kidneys, intestines, sweat and mammary glands.

    Indications:

    Inflammatory and infectious diseases of the skin, abrasions, cuts, microtrauma, wounds; inflammatory infiltrates; treatment of the edges of wounds, skin before injections, punctures, catheterization.

    Contraindications:

    Hypersensitivity, thyrotoxicosis, herpetiform dermatitis.

    Carefully:

    There is no information.

    Pregnancy and lactation:

    Before use, consult a physician.

    Dosing and Administration:

    External, lubricate the affected and subject to treatment areas of the skin.

    Side effects:

    Skin irritation, with prolonged use on extensive wound surfaces - iodism (rhinitis, urticaria, Quincke's edema, salivation, lacrimation, acne), allergic reactions (skin itching).

    Overdose:

    When breathing in vapors, defeat of the upper respiratory tract (burn, laryngobrachospasm); when concentrated solutions get inside - severe burns of the digestive tract, development of hemolysis, hemoglobinuria; The lethal dose is about 3 g.

    Treatment: wash the stomach with a 0.5% sodium thiosulfate solution, iv injected sodium thiosulfate 30% to 300 ml.

    Interaction:

    Pharmaceutically incompatible with essential oils, solutions of ammonia, white sedimentary mercury (an explosive mixture is formed).

    Alkaline or acidic environment, the presence of fat, pus, blood weakens antiseptic activity.

    Special instructions:

    When combined with yellow mercury ointment, the formation of mercury iodide, which has a cauterizing effect, is possible.

    Form release / dosage:Solution for external use [alcohol], 5%.
    Packaging:

    Bottles of 1, 5, 10, 18, 20 kg.

    Flask-droppers, bottles of glass, polymeric bottles, bottles with lid-pomazkom for 10, 15, 20, 25 ml; bottles of 10 ml.

    The device is a polymer with a porous rod (pharmacograph) of 3, 5 ml.

    Storage conditions:

    In the dark place at a temperature of at least 0 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years (in bottles, bottles-droppers and bottles), 1 year (in pharmacology).

    Do not use after the time specified on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LS-000100
    Date of registration:24.03.2010
    Expiration Date:Unlimited
    The owner of the registration certificate:SAMARAHEDPROM, JSC SAMARAHEDPROM, JSC Russia
    Manufacturer: & nbsp
    Representation: & nbspSAMARAHEDPROM, JSCSAMARAHEDPROM, JSC
    Information update date: & nbsp17.11.2017
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