Iodine - instructions for use, dose, side effects, contraindications

Antiseptic. The main active substance is molecular iodine, which has an antiseptic property. When applied to large areas of the skin iodine has a resorptive effect: actively affects the metabolism, enhances the processes of dissimilation, participates in the synthesis of thyroxine and triiodothyronine, has a proteolytic effect. Alcohol slows the excretion of iodine and reduces its irritating effect on tissues. It has a bactericidal effect on both gram-positive and gram-negative flora (most active in streptococcal flora and Escherichia coli), as well as pathogenic fungi and yeast.A more stable flora is staphylococcus, but with prolonged use of the drug in 80% of cases, staphylococcal flora is suppressed. Pseudomonas aeruginosa is stable. The drug is low toxicity.

Pharmacokinetics:

Upon contact with the skin, it is converted into iodides by 30%, and the rest into active iodine. Partially absorbed. The absorbed part penetrates into tissues and organs, is selectively absorbed by the thyroid gland. Is allocated kidneys (mainly), intestines, sweat glands, with milk during lactation.

Indications:

Inflammatory and infectious diseases of the skin, abrasions, cuts, microtrauma, wounds; myositis, neuralgia, inflammatory infiltrates; treatment of the edges of wounds, skin before injections, punctures, catheterization.

Contraindications:

Hypersensitivity, thyrotoxicosis, herpetiform dermatitis.

Dosing and Administration:Outwardly. Lubricate affected or subject to treatment areas of the skin.

Side effects:

Skin irritation, allergic reactions (itchy skin); with prolonged use on extensive wound surfaces - iodism (rhinitis, urticaria, Quincke's edema, salivation, lacrimation, acne).

Interaction:

Pharmaceutically incompatible with essential oils, solutions of ammonia, white sedimentary mercury (an explosive mixture is formed).

Alkaline or acidic environment, the presence of fat, pus, blood weakens antiseptic activity.

Special instructions:

Light and temperature above 40 ° C accelerate the decay of active iodine.

The drug should have a dark brown color. Discoloration of the solution indicates the destruction of the complex with the transition of active iodine to iodide ion and a decrease in the effectiveness of the preparation.

Form release / dosage:

Solution for external use alcohol, 5%.

Packaging:

For 10 ml in glass bottles with a screw neck of brown glass, sealed with plastic lids.

Each bottle, together with the instructions for use, is placed in a pack of cardboard.

It is allowed to put the vials together with an equal number of instructions for use in a group package.

For 17 kg in a glass bottle (for production departments of pharmacies).

Storage conditions:Store in a dark place at a temperature of 0 to 20 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-001902/10

Date of registration:12.03.2010

Expiration Date:Unlimited

The owner of the registration certificate:MOSCOW PHARMACEUTICAL FACTORY, CJSC MOSCOW PHARMACEUTICAL FACTORY, CJSC Russia

Manufacturer: & nbsp

MOSCOW PHARMACEUTICAL FACTORY, CJSC Russia

Representation: & nbspMOSCOW PHARMACEUTICAL FACTORY MOSCOW PHARMACEUTICAL FACTORY Russia

Information update date: & nbsp17.11.2017

Illustrated instructions

Instructions

Iodine (Iodum)