Iodine - instructions for use, dose, side effects, contraindications

Antiseptic. The main active substance is molecular iodine, which has an antiseptic property. When applied to large areas of the skin iodine has a resorptive effect: actively affects the metabolism, enhances the processes of dissimilation, participates in the synthesis of thyroxine and triiodothyronine, has a proteolytic effect. Alcohol slows the excretion of iodine and reduces its irritating effect on tissues.

It has a bactericidal effect on both gram-positive and gram-negative flora (most active on streptococcal flora and E. coli), as well as pathogenic fungi and yeast; A more stable flora is staphylococcus, but with prolonged use of the drug in 80% of cases, staphylococcal flora is suppressed. Pseudomonas aeruginosa is stable. The drug is low toxicity.

Pharmacokinetics:

Upon contact with the skin, it is converted into iodides by 30%, and the rest into active iodine. Partially absorbed. The absorbed part penetrates into tissues and organs, is selectively absorbed by the thyroid gland. It is allocated by kidneys (mainly), intestines, sweat glands, with milk during lactation.

Indications:

Inflammatory and infectious diseases of the skin, abrasions, cuts, microtrauma, wounds; myositis, neuralgia, inflammatory infiltrates; treatment of the edges of wounds, skin before injections, punctures, catheterization.

Contraindications:

Hypersensitivity, thyrotoxicosis, herpetiform dermatitis.

Dosing and Administration:

External, lubricate the affected or subject to treatment areas of the skin.

Side effects:

Skin irritation, allergic reactions (itchy skin); with prolonged use on extensive wound surfaces - iodism (rhinitis, urticaria, Quincke's edema, salivation, lacrimation, acne).

Overdose:

When inhaled vapors of iodine - the defeat of the upper respiratory tract (burn, laryngobrachospasm); concentrated solutions inside - severe burns of the digestive tract, development of hemolysis, hemoglobinuria.

For the treatment of an overdose when ingested, sodium thiosulfate in the form of a 10% solution of 2-3 g per reception.

Interaction:

Pharmaceutically incompatible with essential oils, solutions of ammonia, white sedimentary mercury (an explosive mixture is formed).

Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity.

Special instructions:

Light and temperature above 40 ° C accelerate the decay of active iodine.

The drug should have a dark brown color. Discoloration of the solution indicates the destruction of the complex with the transition of active iodine to iodide ion and a decrease in the effectiveness of the preparation.

When combined with yellow mercury ointment, the formation of mercury iodide, which has a cauterizing effect, is possible.

Form release / dosage:Solution for external use alcohol, 5%.

Packaging:

For 10 ml of the drug in flasks of orange glass type PV and FSY or FVL-10, FSLya-10;

on 10,25, 100 ml of the preparation into flasks of orange glass of type FV;

10, 15, 25 ml of the preparation into bottles of polyethylene terephthalate of dark brown color.

By 9, 18 kg "angro" of the drug in a bottle of glass type BTV, packed in black light-protective paper;

on 4500 g "angro" preparation in bottles made of polyethylene terephthalate of dark brown color or packed in black light-protective paper.

Each vial of 10, 15, 25 or 100 ml, along with the instructions for medical use, is placed in a cardboard box. It is allowed to put the full text of instructions for medical use on a cardboard pack.

Vials of 10, 15, 25 or 100 ml without a bundle with the appropriate number of instructions for medical use are placed in a group container.

Storage conditions:

In the dark place at a temperature of at least 0 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use the product after the expiration date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-003836/09

Date of registration:21.05.2009

Expiration Date:Unlimited

The owner of the registration certificate:KIROVSKAYA PHARMACEUTICAL COMPANY, LTD. KIROVSKAYA PHARMACEUTICAL COMPANY, LTD. Russia

Manufacturer: & nbsp

KIROVSKAYA PHARMACEUTICAL FACTORY, OJSC Russia

Representation: & nbspKIROVSKAYA PHARMACEUTICAL FACTORY, OJSCKIROVSKAYA PHARMACEUTICAL FACTORY, OJSC

Information update date: & nbsp17.11.2017

Illustrated instructions

Instructions

Iodine (Iodum)