Iodine - instructions for use, dose, side effects, contraindications

Antiseptic. The main active substance is molecular iodine, which has an antiseptic property. When applied to large areas of the skin iodine has a resorptive effect: actively affects the metabolism, enhances the processes of dissimilation, participates in the synthesis of thyroxine and triiodothyronine, has a proteolytic effect. Alcohol slows the excretion of iodine and reduces its irritating effect on tissues. It has a bactericidal effect on both gram-positive and gram-negative flora (most active in streptococcal flora and Escherichia coli), as well as pathogenic fungi and yeast. A more stable flora is staphylococcus, but with prolonged use of the drug in 80% of cases, staphylococcal flora is suppressed. Pseudomonas aeruginosa is stable. The drug is low toxicity.

Pharmacokinetics:

Upon contact with the skin, it is converted into iodides by 30%, and the rest into active iodine. Partially absorbed. The absorbed part penetrates into tissues and organs, is selectively absorbed by the thyroid gland. It is allocated by kidneys (mainly), intestines, sweat glands, with milk during lactation.

Indications:

Inflammatory and infectious diseases of the skin, abrasions, cuts, microtrauma, wounds; myositis, neuralgia, inflammatory infiltrates; treatment of the edges of wounds, skin before injections, punctures, catheterization.

Contraindications:

Hypersensitivity, thyrotoxicosis, herpetiform dermatitis.

Dosing and Administration:

External, lubricate the affected or subject to treatment areas of the skin.

Side effects:

Skin irritation, allergic reactions (itchy skin); with prolonged use on extensive wound surfaces - iodism (rhinitis, urticaria, Quincke's edema, salivation, lacrimation, acne).

Interaction:

Pharmaceutically incompatible with essential oils, solutions of ammonia, white sedimentary mercury (an explosive mixture is formed).

Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity.

Special instructions:

Light and temperature above 40 ° C accelerate the decay of active iodine.

The drug should have a dark brown color. Discoloration of the solution indicates the destruction of the complex with the transition of active iodine to iodide ion and a decrease in the effectiveness of the preparation.

Form release / dosage:Solution for external use (alcohol), 5%.

Packaging:

To 10, 15, 25 ml in bottles of orange glass with a screw mouth, sealed with plastic caps and caps screwed plastic;

10 ml into glass bottles with a screw neck with closures for an alcohol solution of iodine and ammonia solution;

10 ml in glass bottles with a screw mouth, sealed with polyethylene threaded caps with sealing element and brush;

10, 15, 25 ml into polyethylene terephthalate bottles, capped with screwed polyethylene caps with perforations.

Each bottle, along with the instruction for use, is placed in a pack of cardboard or placed in a group package with an equal number of instructions for use.

Storage conditions:

In the dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after the time specified on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-001558/08

Date of registration:14.03.2008

Expiration Date:Unlimited

The owner of the registration certificate:DRUGSTORE FARMICON, LTD. DRUGSTORE FARMICON, LTD. Russia

Manufacturer: & nbsp

DRUGSTORE FARMICON, LTD. Russia

Representation: & nbspDRUGSTORE FARMICON, LTD. DRUGSTORE FARMICON, LTD.

Information update date: & nbsp17.11.2017

Illustrated instructions

Instructions

Iodine (Iodum)