Iodine - instructions for use, dose, side effects, contraindications

Antiseptic. The main active substance is molecular iodine, which has an antiseptic property. When applied to large areas of the skin iodine has a resorptive effect: actively affects the metabolism, enhances the processes of dissimilation, participates in the synthesis of thyroxine and triiodothyronine. Ethyl alcohol slows the excretion of iodine and reduces its irritating effect on the tissue. Has a bactericidal effect on both gram-positive and gram-negative flora (most active - on Streptococcus spp. and Escherichia coli), as well as pathogenic fungi and yeast. A more sustainable flora is Staphylococcus spp. However, with prolonged use of the drug in 80% cases of staphylococcal flora suppression. Pseudomonas aeruginosa is stable. The drug is low toxicity.

Pharmacokinetics:

In case of skin contact, take 30% converted into iodides, and the rest into active iodine. Partially absorbed. The absorbed part penetrates into tissues and organs, is selectively absorbed by the thyroid gland. It is excreted by the kidneys (mainly), intestines, sweat glands, with breast milk during lactation.

Indications:

Inflammatory and infectious diseases of the skin, abrasions, cuts, microtrauma, wounds; myositis, neuralgia, inflammatory infiltrates; treatment of the edges of wounds, skin before injections, punctures, catheterization.

Contraindications:

Hypersensitivity, thyrotoxicosis, herpetiform dermatitis.

Pregnancy and lactation:

Application in accordance with the instructions is possible.

Dosing and Administration:

External, lubricate the affected or subject to treatment areas of the skin. When treating the surgical field, the skin is twice wiped with a sterile gauze pad moistened in solution. Total processing time 4-6 min.

Side effects:

Skin irritation, allergic reactions (itchy skin); with prolonged use on extensive woundsurfaces - iodism (rhinitis, urticaria, Quincke's edema, excessive salivation, lacrimation, acne).

Overdose:

In case of an overdose, there may be phenomena of iodism, irritation, burns.

Interaction:

Pharmaceutically incompatible with essential oils, ammonia solutions; with white sedimentary mercury (mercury amidochloride) - an explosive mixture is formed.

Special instructions:

Light and temperature above 40 ° C accelerate the decay of active iodine.

The drug should have a dark brown color. Discoloration of the solution indicates the destruction of the complex with the transition of iodine to iodide ion and a decrease in the effectiveness of the preparation.

Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity.

Effect on the ability to drive transp. cf. and fur:

The use of the drug according to the instructions for medical use does not render negative impact on the performance of potentially hazardous activities requiring special attention and quick reactions.

Form release / dosage:

Solution for external use [alcohol], 5%.

Packaging:

For 10, 25 ml in bottles of orange glass with a screw mouth, sealed with polymer plugs and polymeric screw caps.

10 ml in bottles of orange glass with a screw mouth, sealed with polymeric screw caps.

For 10 ml in bottles of orange glass with a screw mouth, sealed with polymeric screw caps, or polymeric screw caps with pomat.

For 10, 15, 25 ml in bottles of polyethylene terephthalate, sealed with caps of polymeric screw, or polymeric screw caps with pomat.

For 4500 ml in bottles of polyethylene terephthalate, sealed with polymeric screw caps (for hospitals).

For 1000 ml in a bottle of orange glass with a screw mouth, sealed with polymeric screw caps (for hospitals).

By 9.0 and 18.0 kg in a glass bottle with a screw neck, sealed with screwed polymer caps with gaskets (for hospitals).

Vials (bottles), together with an equal number of instructions for use, are placed in a group box of corrugated cardboard.

Storage conditions:

In the dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after the time specified on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LP-000440

Date of registration:28.02.2011

Expiration Date:Unlimited

The owner of the registration certificate:TULA PHARMACEUTICAL FACTORY, LTD. TULA PHARMACEUTICAL FACTORY, LTD. Russia

Manufacturer: & nbsp

TULA PHARMACEUTICAL FACTORY, LTD. Russia

Representation: & nbspTULA PHARMACEUTICAL FACTORY, LTD.TULA PHARMACEUTICAL FACTORY, LTD.

Information update date: & nbsp17.11.2017

Illustrated instructions

Instructions

Iodine (Iodum)