Aminosol-Neo is a combined preparation for parenteral nutrition, which contains essential and non-essential amino acids in a balanced ratio. All amino acids are in L-form, which ensures the possibility of their direct participation in the biosynthesis of proteins.
Contains eight essential amino acids (not synthesized in the human body): L-isoleucine, L-leucine, L-lysine, L-methionine, L-phenylalanine, L-treonine, L-tryptophan and L-valine. The conditionally interchangeable ones are considered L-arginine and L- histidine. Conditionally interchangeable amino acids are synthesized in the body; However, in some pathological conditions (for example, renal and hepatic insufficiency) and in young children, their concentration does not reach the required level.
L-arginine participates in the cycle of conversion of ammonia to urea, binding toxic ammonium ions, which are formed during the catabolism of proteins in the liver. L-black acid is necessary for regeneration L-arginine in this process and as an energy source for urea synthesis.
L-isoleucine, L-leucine and L-valine - essential amino acids with branched side chains - are actively involved in the synthesis of proteins, especially in muscle tissue, play a role in the energy and metabolism of nerve cells. Participate in the formation and storage of glycogen, the formation of hemoglobin, the synthesis of pantothenic acid. They contribute to the restoration of bone and muscle tissue, skin, which is especially important in the early postoperative period.
Amino acids containing aromatic rings are represented by Lphenylalanine and L- tyrosine in a small and safe amount (due to the potential for cerebro-toxic effects at high concentrations). Mainly the concentration minimization is extended to L-tyrosine, one of the derivatives of which is octopamine - a false neurotransmitter, which has a toxic effect on the central nervous system.
L-phenylalanine is involved in the production of collagen and connective tissues, is involved in the formation of neurotransmitters, stimulates the thyroid gland to produce thyroid hormones,is involved in the transmission of dopamine, helps the formation of insulin, papain, melanin, epinephrine, norepinephrine, dopamine, thyroxine and triiodothyronine.
L-tryptophan participates in the maintenance of nitrogen equilibrium in metabolic processes, acts of excitation and inhibition, as well as the transformation of one type of energy into another. It stimulates the growth of the level of growth hormone in the blood, participates in the synthesis of serotonin, one of the most important neurotransmitters. Formed from L-tryptophan a nicotinic acid is an important component in the energy exchange.
The nitrogen content for the 10% solution is 16.2 g / l, for 15% - 25.7 g / l.
Amino acids in a 10% solution are 100.0 g / 1000 ml, in 15% - 150 g / 1000 ml.