Active substanceAscorbic acid + DextroseAscorbic acid + Dextrose
Dosage form: & nbsppills
Composition:

Composition per one tablet

Ascorbic acid - 100 mg, dextrose monohydrate - 877 mg.

Excipients: calcium stearate - 6 mg, stearic acid - 16.3 mg, talc - 0.7 mg.

Description:Tablets are white, flat-cylindrical with a facet and a risk.
Pharmacotherapeutic group:Vitamin
ATX: & nbsp

A.11.G.B   Ascorbic acid in combination with other drugs

Pharmacodynamics:

Ascorbic acid plays an important role in the regulation of oxidation-reduction processes, carbohydrate metabolism, blood clotting, tissue regeneration, and improves the body's resistance. Ascorbic acid (vitamin C) is not formed in the human body, but comes only with food. With a balanced and nutritious diet, a person does not experience a deficiency in vitamin C.

Indications:Prevention and treatment of hypo- and vitamin deficiency Vitamin C. Providing increased body requirement for vitamin C during growth, pregnancy, gbreastfeeding, with increased physical and mental stress, fatigue, stressful conditions, during recovery after long and severe diseases.
Contraindications:

Hypersensitivity to the components of the drug. Do not administer large doses to patients with increased blood coagulability,thrombophlebitis and a tendency to thrombosis, as well as diabetes and conditions accompanied by high blood sugar.

Dosing and Administration:

The drug is taken orally after a meal. Before use, it can be ground.

With the preventive purpose of appoint: adults - 50-100 mg / day.

During pregnancy and lactation, 300 mg / day for 10-15 days, then 100 mg / day.

With a therapeutic purpose appoint: adults - 50-100 mg 3-5 times a day, children 50-100 mg 2-3 times a day.

The timing of treatment depends on the nature of the and the course of the disease and are recommended by a doctor.

Side effects:

Allergic reactions to the components of the drug are possible.

Interaction:

Ascorbic acid increases absorption of penicillin and iron. Increases the concentration in the blood of tetracyclines; in a dose of 1 g / day increases the bioavailability of ethinyl estradiol (including those included in oral contraceptives). Reduces the effectiveness of heparin and indirect anticoagulants. Acetylsalicylic acid, oral contraceptives, fresh juices and alkaline draw reduce the absorption and absorption of ascorbic acid.

With simultaneous use with acetylsalicylic acid, urinary excretion of ascorbic acid increases and the excretion of acetylsalicylic acid decreases.Increases the risk of developing crystalluria in the treatment of salicylates and sulfonamides short acts, slows the excretion of kidney acids, increases the excretion of drugs that have an alkaline reaction (including alkaloids), reduces the concentration of oral contraceptives in the blood.

Increases the total clearance of ethanol, which in turn reduces the concentration of ascorbic acid in the body.

With simultaneous use reduces the chronotropic effect of isoprenaline.

With long-term use or use in high doses, break down, the interaction of disulfiram-ethanol.

In high doses increases the excretion of mexiletine by the kidneys.

Barbiturates and primidon increase the excretion of ascorbic acid in the urine.

Reduces the therapeutic effect of antipsychotic drugs (neuroleptics) - phenothiazine derivatives, tubular reabsorption of amphetamine and tricyclic antidepressants.

Special instructions:

In connection with the stimulating effect of ascorbic acid on the formation of glucocorticosteroid hormones, it is necessary to monitor the function of the adrenals and arterial pressure.With prolonged administration of large doses, oppression of the insulin function of the pancreas is possible, therefore, during the treatment, the functional capacity of the pancreas must be controlled. Persons with a gluten-6-phosphatehydrogase deficiency should take the drug with caution.

Form release / dosage:Tablets 100 mg + 877 mg.
Packaging:For 30 or 40 tablets in cans of polymeric. For 10 tablets in a contour non-jawed package. Each bank along with the instruction for use is put in a bundle or 32 cans along with the corresponding number of instructions for use are placed in a group package. 380 contour non-jammed packages together with the corresponding number of instructions for use are placed in a shipping container.
Storage conditions:

At a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

1 year.

Do not use the expiration date printed on the package.

Terms of leave from pharmacies:Without recipe
Registration number:P N001671 / 01
Date of registration:08.10.2008
Expiration Date:Unlimited
The owner of the registration certificate:PHARMSTANDART-UFIM VITAMIN FACTORY, OJSC PHARMSTANDART-UFIM VITAMIN FACTORY, OJSC Russia
Manufacturer: & nbsp
Information update date: & nbsp19.09.2017
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