Enter slowly! Piracetam solutions are injected intravenously at a rate of 30-40 drops per minute.
Bolus intravenous administration (for example, with the withdrawal of withdrawal syndrome with alcoholism, emergency treatment of sickle cell anemia, etc.) is performed for at least 2 minutes, the daily dose is then divided into several injections (2-4) at regular intervals so , so that the dose for one administration does not exceed 3 g. Parenteral administration of piracetam is prescribed when it is not possible to use oral medication (tablets, capsules, oral solution), for example, if swallowing is difficult or when the patient t is in a coma.
When the opportunity arises, they switch to oral administration of piracetam. The duration of treatment is determined by the doctor depending on the disease and taking into account the dynamics of the symptoms.
With the symptomatic treatment of chronic psychoorganic syndrome, depending on the severity of symptoms, appoint 2.4-4.8 g / day.
In the treatment of cerebrovascular disorders (stroke) appoint 4.8 - 12 g / day.
In the treatment of coma, as well as difficulties in perception in people with brain trauma the initial dose is 9-12 g / day, supporting - 2 g / day. Treatment continues for at least 3 weeks.
With alcohol withdrawal syndrome - 12 g / day. Supportive dose of 2.4 g / day.
Treatment of dizziness and related disorders of balance 2,4-4,8 g per day, the course is 10-15 days.
With cortical myoclonia treatment starts with a dose of 7.2 g / day, every 3-4 days the dose is increased by 4.8 g / day until the maximum dose of 24 g / day is reached. Treatment continues throughout the period of the disease. Every 6 months. attempts should be made to reduce the dose or discontinue the drug, gradually reducing the dose by 1.2 g / day every 2 days. In the absence of effect or a slight therapeutic effect, treatment is discontinued.
With sickle-cell anemia The daily prophylactic dose is 160 mg / kg of body weight divided into four equal doses. During the crisis, 300 mg / kg.
Children. The only indication is dyslexia in children older than 8 years (as part of complex therapy). The escatropyl is prescribed in a dose of 30-50 mg / kg / day.
Dosing to patients with impaired renal function.
Because the piracetam is excreted from the body by the kidneys, care should be taken when treating patients with renal insufficiency in accordance with this dosing regimen.
| Renal insufficiency | Creatinine clearance (ml / min) | Dosing |
| Absent | >80 | Usual Dose |
| Lightweight | 50-79 | 2/3 of the usual dose in 2-3 injections |
| Average | 30-49 | 1/3 of the usual dose in 2 injections |
| Heavy | 20-30 | 1/6 of the usual dose, once |
| The final stage | <20 | contraindicated |
Elderly, the dose is corrected in the presence of kidney failure. With prolonged therapy, it is necessary to monitor the functional state of the kidneys.
Dosing to patients with impaired liver function.
Patients with a dysfunction of the liver do not need a dose adjustment. If the renal and hepatic functions are impaired simultaneously, the dosing is performed according to the scheme given (see section "Dosing to patients with impaired renal function").