Lugol - instructions for use, doses, side effects, contraindications

Iodine-containing antiseptic. The main active substance is molecular iodine, Antiseptic (bactericidal action against gram-positive and gram-negative flora, as well as pathogenic fungi and yeast, is more resistant Staphylococcus aureus, but long-term use of the drug in 80% of cases there is suppression of staphylococcal flora, resistant Pseudomonas aeruginosa) and the irritant effect. When applied to large areas of the skin iodine has a resorptive effect: participates in the synthesis of T3 and T4.

Potassium iodide improves the dissolution of iodine in water.

Glycerol has a softening effect.

The drug is low toxicity.

Pharmacokinetics:

In the case of spray "Lugol" at recommended doses, iodine resorption through the skin and the oral mucosa is negligible. Upon contact with mucous membranes, it is converted to iodides by 30%. If swallowed accidentally iodine quickly absorbed. The absorbed part penetrates well into tissues and organs, accumulates in the tissues of the thyroid gland. It is excreted by the kidneys (mainly), to a lesser extent with caloric masses and with sweat. Penetrates the milk of lactating women.

Indications:

Infectious and inflammatory diseases of the oral and pharyngeal mucosa in adults and children.

Contraindications:

Decompensated liver and kidney disease, hypersensitivity to iodine or other components of the drug

Carefully:Dhyperthyroidism, herpetiform dermatitis, children under 12 years of age.

Pregnancy and lactation:

Use during pregnancy is contraindicated. The drug is a potential hazard to the fetus, if used by women during the 2-3 trimester of pregnancy for more than 4 days.

Iodine penetrates into the mother's milk and potentially has an effect on thyroid function in children who are breastfeeding. Use in breastfeeding is possible if the potential benefit to the mother exceeds the possible risk to the child. It is necessary to consult a doctor.

Dosing and Administration:

The drug is applied locally 4-6 times a day for irrigation of the oral mucosa, pharynx, throat, spraying the solution with a single push of the spray head.

The injection of this drug is point and the nebulizer, depending on the disease, should be directed directly into the inflammatory focus (see Fig.).

At the time of injection, it is recommended to hold your breath.

Avoid contact with eyes. If this happens, the eyes should be rinsed with plenty of water or a solution of sodium thiosulfate.

If a new medicine package is used, remove the protective cap, put the spray head with the tip and press the spray head several times.

After using the product, it is not recommended to remove the spray head with the tip for the following reasons:

- it is difficult to remove the spray head with a tip (which prevents accidental leakage of the preparation), there is a great risk of getting dirty during removal, and since the preparation contains iodine, these spots are difficult to remove;

- It is not recommended to remove the spray head with a tip to avoid contamination of the plastic tubing and the spray pump;

- it is not desirable to contact the preparation with a damp surface - the tip should not be washed from the inside (it is sufficient to wash the tip with hot water from the outside or wipe with alcohol solution).

Side effects:

Allergic reactions.

With prolonged use - the phenomenon of "iodism": rhinitis, hives, angioedema, salivation, lacrimation, acne.

If the drug exhibits this or other side effects, consult a doctor or pharmacist.

Overdose:

Symptoms: irritation of the upper respiratory tract (burn, laryngobrachospasm); when ingested - mucous digestive tract, development of hemolysis, hemoglobinuria; a lethal dose - about 3 grams (about 6 flasks of spray).

Treatment: gastric lavage with a 0.5% solution of sodium thiosulfate, sodium bicarbonate solutions, intravenously injected sodium thiosulfate 30% to 300 ml.

Interaction:

Iodine is inactivated by sodium thiosulfate. Contained in the preparation iodine oxidizes metals, which can lead to spoilage of metal objects.

Pharmaceutically incompatible with essential oils, ammonia solutions.

Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity.

In the case of Lugol spray application inside, the action of drugs suppressing the thyroid gland function may decrease, and also the thyroid function indices can change.

Iodine preparations can enhance the irritating effect of some drugs (eg, acetylsalicylic acid) on the mucous membranes of the gastrointestinal tract.

Special instructions:

Sunlight and temperatures above 40 ° C accelerate the decay of active iodine.

Form release / dosage:

Solution for topical application, 1%.

Packaging:

To 20 ml in a bottle of dark glass complete with a nebulizer, protective transparent polyethylene cap and nozzle.

Each bottle together with a nebulizer, cap, nozzle and instruction for medical use is placed in a cardboard pack.

Storage conditions:

Store in a dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-003408

Date of registration:13.01.2016

Expiration Date:13.01.2021

The owner of the registration certificate:Danske Intergroup, TOODanske Intergroup, TOO United Kingdom

Manufacturer: & nbsp

RIGAS FARMACEITISKA FABRIKA A / S Latvia

Representation: & nbspMedicoLight, LLCMedicoLight, LLC

Information update date: & nbsp20.03.2018

Illustrated instructions

Instructions

Lugol (LUGOL)