Lugol - instructions for use, doses, side effects, contraindications

Pharmacodynamics:The main active substance is molecular iodine, which has an antiseptic and local irritant effect. It has bactericidal action against gram-negative and gram-positive flora, and also acts on pathogenic fungi (including yeast); Staphylococcus spp. are more resistant to iodine, but with prolonged use of the drug in 80% of cases, staphylococcal flora is suppressed; Pseudomonas aeruginosa is resistant to the action of the drug. When applied to large areas of the skin and mucous membranes iodine has a resorptive effect: participates in the synthesis of T3 and T4, has a proteolytic effect. Potassium iodide improves the dissolution of iodine in water. Glycerol has a softening effect. The drug is low toxicity.

Pharmacokinetics:

In case of application of the drug in recommended doses, resorption of iodine through the skin and mucous membranes of the oral cavity is insignificant. Upon contact with mucous membranes, it is converted to iodides by 30%.If swallowed accidentally iodine quickly absorbed. The absorbed part penetrates well into the organs and tissues (including the tissues of the thyroid gland). It is excreted mainly by the kidneys, to a lesser extent by the intestines and with sweat. Penetrates into breast milk.

Indications:

Infectious and inflammatory diseases of the oral and pharyngeal mucosa in adults and children.

Contraindications:

Decompensated diseases of the liver and kidneys.

Hypersensitivity to iodine and other components of the drug.

Carefully:

Hyperthyroidism, herpetiform dermatitis, children under 12 years.

Pregnancy and lactation:

Use during pregnancy is contraindicated.

Iodine penetrates into the mother's milk and potentially has an effect on thyroid function in children who are breastfeeding. Application during breastfeeding is possible if the potential benefit to the mother exceeds the possible risk to the child. It is necessary to consult a doctor.

Dosing and Administration:

Locally.

Apply 4-6 times a day for irrigation of the mucous membrane of the oral cavity, pharynx, throat, carrying out the application of the preparation with a single push of the spray head.

Injection of the drug is point and the nebulizer depending on the disease should be directed directly to the focus of inflammation.

At the time of injection, it is recommended to hold your breath.

If a new medicine package is used, remove the protective cap, put the spray head with the tip and press the spray head several times. After using the product, it is not recommended to remove the head of the nebulizer with the tip.

Avoid contact with eyes. If this happens, the eyes should be washed with a large amount of water or a solution of sodium thiosulfate.

If the symptoms of inflammation do not decrease or worsen after 2-3 days of therapy, then it is necessary to consult a doctor. Not recommended for long (more than 2 weeks) use.

Side effects:

Allergic reactions.

With prolonged use: the phenomenon of "iodism", rhinitis, urticaria, angioedema, salivation, lacrimation, acne.

If the drug exhibits this or other side effects, it is necessary to consult a doctor.

Overdose:

Symptoms: irritation of the upper respiratory tract (burn, laryngo-, bronchospasm); at ingestion - irritation of the mucous membranes of the gastrointestinal tract, hemolysis, hemoglobinuria; lethal dose - about 3 g.

Treatment: gastric lavage with a 0.5% solution of sodium thiosulfate, sodium bicarbonate solutions, intravenously injected sodium thiosulfate 30% to 300 ml.

Interaction:

Iodine is inactivated by sodium thiosulfate.

Contained in the preparation iodine oxidizes metals, which can lead to damage to metal tools and surfaces.

Pharmaceutically incompatible with essential oils, ammonia solutions.

Alkaline or acid reaction, the presence of fat, pus, blood weakens antiseptic activity.

In the case of getting the drug inside, the action of drugs suppressing the thyroid gland function may decrease, and also the thyroid function indices can change.

Iodine preparations can enhance the irritating effect of certain drugs (including acetylsalicylic acid) on the mucosa of the gastrointestinal tract.

Special instructions:

It is necessary to avoid regular use in patients with hyperthyroidism (thyrotoxicosis).

Children under 12 years of age should be consulted with a doctor.

Can affect the results of laboratory data in the study of thyroid hormones.

Sunlight and temperatures above 40 ° C accelerate the decay of active iodine.

Effect on the ability to drive transp. cf. and fur:No data.

Form release / dosage:

Solution for topical application, 1%.

Packaging:

For 25 ml and 50 ml in orange glass bottles with a screw neck for medicines, sealed with a lid with a dispenser complete with a nozzle with a nozzle.

Each bottle together with a sprayer with a tip and instruction for medical use is placed in a pack of cardboard box-type chrome-ersatz.

Storage conditions:

Store in a dark place at a temperature of 2 ° C to 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use the product after the expiration date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LP-003499

Date of registration:14.03.2016

Expiration Date:14.03.2021

The owner of the registration certificate:YUZHFARM, LLC YUZHFARM, LLC Russia

Manufacturer: & nbsp

YUZHFARM, LLC Russia

Representation: & nbspYUZHFARM, LLCYUZHFARM, LLC

Information update date: & nbsp20.03.2018

Illustrated instructions

Instructions

Lugol (Lugol )