Lugol (Lugol)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceIodine + [Potassium iodide + Glycerol]Iodine + [Potassium iodide + Glycerol]
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    • Dosage form: & nbspspray for topical application
    Composition:

    Active substance:

    Iodine - 1 g,

    Excipients:

    Potassium iodide - 2 g,

    Purified water - 3 g,

    Glycerol 85% - 94 g.

    Description:Transparent viscous liquid of red-brown color with the smell of iodine.
    Pharmacotherapeutic group:Antiseptic
    ATX: & nbsp

    D.08.A.G.   Preparations of iodine

    Pharmacodynamics:

    The main active substance is molecular iodine, which has an antiseptic and local irritant effect. It has bactericidal action against gram-negative and gram-positive flora, and also acts on pathogenic fungi (including yeast); Staphylococcus spp. are more resistant to iodine, but with prolonged use of the drug in 80% of cases, staphylococcal flora is suppressed; Pseudomonas aeruginosa is resistant to the action of the drug. When applied to large areas of the skin and mucous membranes iodine has a resorptive effect: participates in the synthesis of T3 and T4,

    Included in the potassium iodide improves the dissolution of iodine in water, and glycerol has a softening effect.

    Pharmacokinetics:

    In case of application of the drug in recommended doses, resorption of iodine through the skin and mucous membranes of the oral cavity is negligible. Upon contact with mucous membranes, it is converted to iodides by 30%.

    If swallowed accidentally iodine quickly absorbed. The adsorbed part penetrates well into tissues and organs, accumulates in the tissues of the thyroid gland. It is excreted by the kidneys (mainly), to a lesser degree with the calves and sweat.Penetrates the milk of lactating women.

    Indications:

    Infectious and inflammatory diseases of the oral and pharyngeal mucosa in adults and children.

    Contraindications:

    Hypersensitivity to iodine or other components of the drug, decompensated liver and kidney disease.

    Carefully:

    Hyperthyroidism (thyrotoxicosis), herpetiform dermatitis, children under 12 years.

    Pregnancy and lactation:

    The use during pregnancy is contraindicated. Iodine penetrates into the mother's milk and can potentially affect the function of the thyroid gland in children who are breastfeeding. Use in breastfeeding is possible if the potential benefit to the mother exceeds the potential risk to the child. It is necessary to consult a doctor.

    Dosing and Administration:

    The drug is applied locally 4-6 times a day for irrigation of the mucous membrane of the mouth, pharynx, throat, spraying the spray with a single push of the spray head. At the time of injection, it is recommended to hold your breath.

    Avoid contact with eyes. If this happens, the eyes should be washed with a large amount of water or a solution of sodium thiosulfate.If the symptoms of inflammation do not decrease or worsen after 2-3 days of therapy, then it is necessary to consult a doctor. Not recommended for long (more than 2 weeks) use.

    Side effects:

    Allergic reactions. With prolonged use - the phenomenon of "iodism": rhinitis, hives, angioedema, salivation, lacrimation, acne.

    If the drug exhibits this or other side effects, consult a physician.

    Overdose:

    Symptoms: irritation of the upper respiratory tract (burn, laryngoblhospasm); when ingested - the mucous membranes of the gastrointestinal tract, the development of hemolysis, hemoglobinuria; a lethal dose-about 3 g (about 300 ml of the drug).

    Treatment: gastric lavage with 0.5% sodium thiosulfate solution, sodium bicarbonate solutions, iv injected sodium thiosulfate 30% to 300 ml.

    Interaction:

    Iodine is inactivated by sodium thiosulfate. Contained in the preparation iodine oxidizes metals, which can lead to spoilage of metal objects. Pharmaceutically incompatible with essential oils, ammonia solutions.Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity. In the case of getting the drug inside, the action of drugs suppressing the thyroid gland function may decrease, and also the thyroid function indices can change. Iodine preparations can enhance the irritating effect of certain drugs (including acetylsalicylic acid) on the mucosa of the gastrointestinal tract.

    Special instructions:Sunlight and temperatures above 40 ° C accelerate the decay of active iodine. It is necessary to avoid regular use in patients with hyperthyroidism (thyrotoxicosis). Children under 12 years of age should be consulted with a doctor. Can affect the results of laboratory data in the study of thyroid hormones.
    Form release / dosage:

    Spray for topical application, 1%.

    Packaging:

    To 25, 30, 50, 60 g in bottles of orange glass, sealed with a lid with a dispenser and complete with a sprayer.

    For 25, 30, 50, 60 g in polymer bottles, sealed with a lid with a dispenser and complete with a sprayer.

    Each bottle together with the instruction for use is placed in a pack of cardboard box.

    Storage conditions:

    In the dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after expiry date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-000119
    Date of registration:28.12.2010 / 08.02.2016
    Expiration Date:Unlimited
    Date of cancellation:2015-12-28
    The owner of the registration certificate:LEKAR, LLC LEKAR, LLC Russia
    Manufacturer: & nbsp
    Representation: & nbspLEKAR, LLCLEKAR, LLCRussia
    Information update date: & nbsp20.03.2018
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