Active substanceIodine + [Potassium iodide + Glycerol]Iodine + [Potassium iodide + Glycerol]
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  • Dosage form: & nbsptopical solution
    Composition:

    Active substance: iodine 1 g;

    Excipients: potassium iodide 2 g, glycerol (glycerol) 85.5 g, purified water 11.5 g.

    Description:

    Transparent syrupy liquid of red-brown color with a smell of iodine.

    Pharmacotherapeutic group:Antiseptic
    ATX: & nbsp

    D.08.A.G.   Preparations of iodine

    Pharmacodynamics:

    The formulation contains iodine, potassium iodide and glycerol. Iodine has a local irritating and antimicrobial effect: it destroys gram-positive and gram-negative bacteria, protozoa, cysts, viruses and some spores. The bactericidal action is strong and manifests itself rapidly (it is mostly predetermined by the molecular iodine). Iodine reacts with dead microorganisms and proteins and its bactericidal effect is weakened due to this.

    Potassium iodide improves the dissolution of iodine ions in water.

    Glycerol has a softening local effect.

    Pharmacokinetics:

    When in contact with the mucous membranes, 30% turns into iodides, and the rest into active iodine.

    Getting inside iodine quickly absorbed and involved in the synthesis of thyroid hormones. From the body iodine in the form of various compounds is removed with urine.
    Indications:

    Infectious and inflammatory diseases of the mucous membranes of the mouth, pharynx and larynx (angular stomatitis, laryngitis,tonsillitis, pharyngitis).

    Contraindications:

    Increased sensitivity of the body to drugs containing iodine, Use during pregnancy and lactation.

    Carefully:

    Decompensated diseases of the liver and kidneys, hyperthyroidism, herpetiform dermatitis.

    Pregnancy and lactation:

    The drug belongs to category D (dangerous to the fetus, if used for longer than a week).

    Iodine penetrates into the mother's milk and can suppress the function of the thyroid gland of a newborn and baby.

    Dosing and Administration:

    Locally. The solution is applied to the inflamed mucous membrane of the oral cavity, pharynx and larynx with a cotton swab, wound on a spatula and moistened in solution, or with the help of a spray nozzle.

    Side effects:

    Allergic reactions.

    With long-term use of the drug or individual intolerance to iodine, iodism can occur: rhinitis, skin rashes like urticaria, acne, salivation, lacrimation, burning in the throat, contact dermatitis, erythema, bronchospasm, nausea, vomiting, and Quincke's edema.

    Overdose:

    Symptoms: irritation of the upper respiratory tract (burn, laryngo-,bronchospasm); when ingested - irritation of the mucous membranes of the gastrointestinal tract, hemolysis, hemoglobinuria; lethal dose - 3 g.

    Treatment: gastric lavage with a 0.5% sodium thiosulfate solution, sodium bicarbonate solutions, intravenously sodium thiosulfate 30% to 300 ml or other solutions with slightly alkaline reaction.

    Interaction:

    Iodine is inactivated by sodium thiosulfate.

    Pharmaceutically incompatible with essential oils, solutions of ammonia, hydrogen peroxide.

    In case of getting the drug inside, the effect of drugs suppressing the function of the thyroid gland can decrease.

    The drug "Lugol solution with glycerin" can enhance the irritating effect of certain drugs, for example, acetylsalicylic acid, on the mucous membrane of the stomach.

    Special instructions:

    Patients suffering from thyroid diseases should carefully use medicines containing iodine.

    Sunlight and temperatures above 40 degrees accelerate the decay of active iodine.

    Do not get into the eyes. If this happens, the eyes should be washed with a large amount of water or a solution of sodium thiosulfate.

    Do not swallow the drug!

    Effect on the ability to drive transp. cf. and fur:

    Does not affect.

    Form release / dosage:

    Solution for topical application.

    Packaging:

    For 25 and 50 g in bottles of orange glass, sealed with polymer caps and polymeric screw caps.

    For 25 and 50 g in bottles-droppers orange glass or in bottles of brown glass with spray nozzles.

    Each bottle or bottle-dropper with instructions for use is placed in a pack of cardboard.

    Storage conditions:

    In the dark place at a temperature above 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after expiry date.

    Terms of leave from pharmacies:Without recipe
    Registration number:P N001598 / 01
    Date of registration:23.07.2008 / 11.09.2012
    Expiration Date:Unlimited
    The owner of the registration certificate:MOSCOW PHARMACEUTICAL FACTORY, CJSC MOSCOW PHARMACEUTICAL FACTORY, CJSC Russia
    Manufacturer: & nbsp
    Representation: & nbspMOSCOW PHARMACEUTICAL FACTORY MOSCOW PHARMACEUTICAL FACTORY Russia
    Information update date: & nbsp21.03.2018
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