Iodine + [Potassium iodide + Glycerol] (Iodum + [Kalii iodidum + Glycerinum])

Pharmacodynamics Pharmacokinetics Indications Carefully Contraindications Dosing and Administration Side effects
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Clinical and pharmacological group: & nbsp

Antiseptics and disinfectants

Included in the formulation
  • Lugol
    spray locally 
    LEKAR, LLC     Russia
  • Lugol
    solution locally 
    ECOLAB, CJSC     Russia
  • Lugol
    spray locally 
    Valentis, ZAO     Republic of Lithuania
  • Lugol
    solution locally 
    Danske Intergroup, TOO     United Kingdom
  • Lugol
    spray locally 
    YUZHFARM, LLC     Russia
  • Lugol solution with glycerol
    solution locally 
    FLORA CAUCASUS, OJSC     Russia
  • Lugol solution with glycerol
    solution locally 
    SAMARAHEDPROM, JSC     Russia
  • Lugol solution with glycerol
    solution locally 
    TULA PHARMACEUTICAL FACTORY, LTD.     Russia
  • Lugol solution with glycerol
    solution locally 
    KIROVSKAYA PHARMACEUTICAL COMPANY, LTD.     Russia
  • Lugol solution with glycerol
    solution locally 
    ROSTOVSKAYA FARMFABRIKA, CJSC     Russia
  • Lugol solution with glycerol
    solution locally 
    YAROSLAVSK PHARMACEUTICAL FACTORY, CJSC     Russia
  • Lugol solution with glycerol
    solution locally 
    TVERSKAYA PHARMACEUTICAL FACTORY, OJSC     Russia
  • Lugol solution with glycerol
    solution locally 
    MOSCOW PHARMACEUTICAL FACTORY, CJSC     Russia
    • Included in the list (Order of the Government of the Russian Federation No. 2782-r of 30.12.2014):

    VED

    ONLS

    АТХ:

    D.08.A.G.   Preparations of iodine

    Pharmacodynamics:
    The main active substance is molecular iodine, which has an antiseptic and local irritant effect.It has bactericidal action against gram-negative and gram-positive flora, and also acts on pathogenic fungi (including yeast); Staphylococcus spp. are more resistant to iodine, but with prolonged use of the drug in 80% of cases, staphylococcal flora is suppressed; Pseudomonas aeruginosa resistant to the action of the drug. When applied to large areas of the skin and mucous membranes iodine has a resorptive effect: participates in the synthesis triiodothyronine and thyroxine.
    Included in the potassium iodide improves the dissolution of iodine in water, and glycerol has a softening effect.
    Pharmacokinetics:In case of application of the drug in recommended doses, resorption of iodine through the skin and mucous membranes of the oral cavity is negligible. Upon contact with mucous membranes, it is converted to iodides by 30%. If swallowed accidentally iodine quickly absorbed. The adsorbed part penetrates well into tissues and organs, accumulates in the tissues of the thyroid gland. It is excreted by the kidneys (mainly), to a lesser degree with the calves and sweat. Penetrates the milk of lactating women.
    Indications:

    For external use: infectious and inflammatory skin lesions, trauma, wounds, myalgia.

    For topical application: andInfectious-inflammatory diseases of the oral and pharyngeal mucosa in adults and children (for example, chronic tonsillitis), atrophic rhinitis, purulent otitis, trophic and varicose ulcers, wounds, infected burns, fresh thermal and chemical burns of I-II degree.

    ICD-10

    X.J00-J06.J02   Acute pharyngitis

    X.J00-J06.J03   Acute tonsillitis

    XI.K00-K14.K05   Gingivitis and periodontal disease

    XI.K00-K14.K12   Stomatitis and related lesions

    Contraindications:Hypersensitivity to iodine or other components of the drug. Pregnancy. Severe liver and kidney disease.
    Carefully:Apply in patients with decompensatedliver and kidney diseases, thyrotoxicosis, herpetiform dermatitis.
    Pregnancy and lactation:It is not recommended to use the drug during pregnancy. Application in the period of breastfeeding is possible if the expected benefit for the mother exceeds the potential risk for the child. It is necessary to consultwith a doctor.
    Dosing and Administration:The drug is applied locally 4-6 times a day for irrigation of the mucous membrane of the mouth, pharynx, throat. Avoid contact with eyes.If this happens, the eyes should be washed with a large amount of water or a solution of sodium thiosulfate.
    Side effects:

    Allergic reactions. With prolonged use - the phenomenon of "iodism": rhinitis, hives, angioedema, salivation, lacrimation, acne.

    If the drug exhibits this or other side effects, it is necessary to consult a doctor.

    Overdose:

    Symptoms: irritation of the upper respiratory tract (burn, laryngoblhospasm); when ingested - the mucous membranes of the gastrointestinal tract, the development of hemolysis, hemoglobinuria; The lethal dose is about 3 g (about 300 ml of the drug).

    Treatment: gastric lavage with 0.5% sodium thiosulfate solution, sodium bicarbonate solutions, intravenously administered sodium thiosulfate 30% to 300 ml.

    Interaction:

    Combination iodine + [potassium iodide + glycerol] is pharmaceutically incompatible with solutions of hydrogen peroxide and with solutions of ammonia.

    Iodine (in combination iodine + [potassium iodide + glycerol]) is inactivated by sodium thiosulfate.

    It is not recommended to use a combination tetracaine + chlorhexidine + ascorbic acid in the form of tablets for resorption and lozenges simultaneously with the drug.

    Special instructions:

    Sunlight and temperatures above 40 ° C accelerate the decay of active iodine.

    Contained in the preparation iodine oxidizes metals, which can lead to spoilage of metal objects.

    Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity.

    Instructions
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