Lugol solution with glycerol (Lugol solution with glycerin)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceIodine + [Potassium iodide + Glycerol]Iodine + [Potassium iodide + Glycerol]
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    • Dosage form: & nbsptopical solution
    Composition:

    At 100 g.

    active substance: iodine 1 g;

    Excipients: potassium iodide 2 g, glycerol 94 g, purified water 3 g.

    Description:Transparent syrupy liquid of reddish-brown color with the smell of iodine.
    Pharmacotherapeutic group:antiseptic
    ATX: & nbsp

    D.08.A.G.   Preparations of iodine

    Pharmacodynamics:

    The main active substance is molecular iodine, which has an antiseptic and local irritant effect. It has bactericidal action against gram-negative and gram-positive flora, and also acts on pathogenic fungi (including yeast); Staphylococcus spp. are more resistant to iodine, but with prolonged use of the drug in 80% of cases, staphylococcal flora is suppressed; Pseudomonas aeruginosa is resistant to the action of the drug. When applied to large areas of the skin and mucous membranes iodine has a resorptive effect: participates in the synthesis of T3 and T4. Included in the potassium iodide improves the dissolution of iodine in water, glycerol has a softening effect.

    Resorption of iodine through the skin and mucous membranes of the mouth is insignificant. Upon contact with mucous membranes, it is converted to iodides by 30%.

    Pharmacokinetics:

    If swallowed accidentally iodine quickly absorbed. The absorbed part penetrates well into the organs and tissues (incl.tissues of the thyroid gland). It is excreted mainly by the kidneys, to a lesser extent by the intestines and with sweat. Penetrates into breast milk.

    Indications:

    Infectious and inflammatory diseases of the mucous membrane of the mouth and pharynx in adults and children.

    Contraindications:

    Hypersensitivity to iodine and other components of the drug. Severe liver and kidney disease.

    Carefully:

    Hyperthyroidism, herpetiform dermatitis. Children under 12 years.

    Pregnancy and lactation:

    Use during pregnancy is contraindicated.

    During breastfeeding, the application is possible if the potential benefit to the mother exceeds the possible risk to the child. It is necessary to consult a doctor.

    Dosing and Administration:

    Locally. Apply 4-6 times a day to lubricate the mucous membrane of the mouth. pharynx, throat. The length of the course of treatment depends on the nature of the disease and its severity. Lubricate the affected area with a moistened swab.

    Side effects:

    Allergic reactions. With prolonged use - the phenomenon of "iodism": rhinitis, hives, angioedema, salivation, lacrimation, acne.

    If side effects occur that are not described in this manual, stop taking the medication and tell your doctor.

    Overdose:

    Symptoms: irritation of the upper respiratory tract (burn, laryngo-, bronchospasm); when ingested - irritation of the mucous membranes of the gastrointestinal tract, hemolysis, hemoglobinuria; lethal dose - about 3 g.

    Treatment: washing the stomach with a 0.5% solution of sodium thiosulfate, sodium bicarbonate solutions, iv sodium thiosulfate 30% to 300 ml.

    Interaction:

    Iodine is inactivated by sodium thiosulfate. Contained in the preparation iodine oxidizes metals, which can lead to damage to metal tools and surfaces. Pharmaceutically incompatible with essential oils, ammonia solutions. Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity. In case of getting the drug inside, the action of drugs that suppress the thyroid gland function may decrease, and the parameters of the thyroid function may change. Iodine preparations can enhance the irritating effect of certain drugs (including acetylsalicylic acid) on the mucosa of the gastrointestinal tract.

    Special instructions:Iodine penetrates into breast milk and can potentially affect the function of the thyroid gland in children who are breastfeeding. If symptoms of inflammation or deterioration persist while using the drug for 2-3 days, you should inform your doctor about it. Not recommended for long-term use (more than 2 weeks). Sunlight and temperatures above 40 ° C accelerate the decay of active iodine.
    Effect on the ability to drive transp. cf. and fur:The use of the drug does not affect the ability to carry out potentially dangerous activities requiring increased concentration of attention and speed of psychomotor reactions (vehicle management, work with moving mechanisms, dispatcher and operator work).
    Form release / dosage:

    Solution for topical application.

    Packaging:

    By 25, 30, 50 g in bottles of orange glass, sealed with stoppers and polymer lids, or lids aluminum; or PET bottles complete with lids for medicines.

    Each bottle, together with the instructions for use, is placed in a pack of cardboard. It is allowed to put the full text of instructions on the pack.

    For hospitals with 100, 200, 300 bottles with an equal number of instructions for use in a cardboard box.

    Storage conditions:

    In the dark place at a temperature of no higher than 15 ° C.

    In a place inaccessible to children.

    Shelf life:

    3 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-001423
    Date of registration:12.01.2012 / 19.09.2017
    Expiration Date:Unlimited
    Date of cancellation:2017-01-12
    The owner of the registration certificate:FLORA CAUCASUS, OJSC FLORA CAUCASUS, OJSC Russia
    Manufacturer: & nbsp
    Representation: & nbspFLORA CAUCASUS, OJSCFLORA CAUCASUS, OJSC
    Information update date: & nbsp20.03.2018
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